目的:通过关联规则方法对焦虑症的治疗方剂进行分析,研究方剂的组成及配伍规律。方法:资料来源于1996年1月至2010年1月收录于中国知网CNKI中医药期刊数据库、学位论文数据库和专利数据库中的焦虑症临床研究文献44篇及专利14项,共纳入54首方剂,建立数据库,用频率描述、广义规则归纳(GRI)关联规则算法及网络图进行数据分析和规则提取。结果:①筛选出常见药物16味;②建立常见药物关系模型,提取药物配伍规则。结论:①酸枣仁、柴胡、茯苓出现频率最高;②柴胡-郁金、酸枣仁-生龙骨、柴胡-白芍-甘草、酸枣仁-茯苓-甘草等是焦虑症治疗方剂中常见的药物配伍规则。
Objective: Analyze the prescriptions of anxiety disorders with association rules,to research the component and compatibility rules of these prescriptions.Methods: The data was from 44 papers and 14 patents of clinical research literature for anxiety disorders in several databases of CNKI,including TCM journal,thesis and patents from Jan 1996 to Jan 2011.There were 54 prescriptions altogether.Created the database,analyzed the prescriptions and extracted compatibility rules with frequency description,GRI association rules and Net model.Results: ①Select 16 herbs mostly used.②Built the association model of these herbs,extract compatibility of them.Conclusion: ①Spine date seed,Chinese thorowax root,poria cocos are the most frequent herbs;②Chinese thorowax-curcuma root,Spine date seed-dragon,s bone,Chinese thorowax root-white peony root-licorice root,Spine date seed-poria cocos-licorice root are the most frequent compatibility rules of the prescriptions in anxiety disorders.