脱氧雪腐镰刀菌烯醇(DON)对食物和饲料的污染已成为全球化的问题,人们也逐渐开始重视饲料污染物DON对动物机体造成的影响。随着科学的不断发展,DON神秘的面纱已被逐渐揭开。近年来的研究证实了随饲料经消化道进入动物机体的DON,在通过改变肠道组织形态学,影响肠道功能的同时,也可通过改变肠道营养物质运输载体、紧密链接蛋白、mRNA转录以及某些炎性物质等的表达,影响肠道营养吸收作用、屏障功能、免疫功能以及渗透作用等,最终导致动物机体产生营养不良、腹泻、呕吐和肠道炎症等不良反应。研究还表明,不同情况下DON对不同的动物肠道可以产生不同的影响。
Deoxynivalenol (DON), as a food and feed contamint, has became a global problem, and people are beginning to pay attention to the impact of DON. With the continuous development of science,DON is being discovered. In recent years, some studies have confirmed that DON is absorbed into the animal body by the way of feed intake, has an influence on intestinal morphology, barrier, immunity, penetration and etc. As consequences,DON has harmful effects on animal health, such as malnutrition, diarrhea, emesis and intestinal inflammation. What's more, DON could influence different animals by different ways.