中文摘要：

目的分析慢性阻塞性肺疾病（COPD）合并阻塞性睡眠呼吸暂停低通气综合征（OSAHS），即重叠综合征患者睡眠呼吸紊乱的临床特点，比较门诊和住院COPD患者的呼吸紊乱情况。方法对Epworth嗜睡量表评分≥10，夜间氧减饱和指数ODI4（每小时血氧饱和度下降4％的次数）≥5的门诊及住院稳定期300例COPD患者进行多导睡眠图监测。结果住院COPD患者的呼吸紊乱程度更严重，住院与门诊COPD合并OSAHS患者在体重指数、血氧饱和度低于90％的时间占总记录时间的百分比、夜间平均血氧饱和度、夜间最低血氧饱和度、呼吸紊乱指数等方面差异显著。此外，住院COPD患者睡眠中心率增快。结论睡眠呼吸紊乱可以影响并加重COPD患者病情。

英文摘要：

Objective To analyze the clinical features of chronic obstructive pulmonary disease （COPD） patients with or without obstructive sleep apnea-hypopnea syndrome （OSAHS） （overlap syndrome）, and compare the status of sleep-disorder breathing between outpatients and inpatients of them. Methods A total of 300 patients with stable COPD were screened for sleep disorder breathing using questionnaire, Epworth sleepiness scale （ESS） and home pulse oximeter testing. Those with ESS≥10 or oxygen desaturation over 4% per hour sleep 〉5 times were under further PSG testing. Results there was significant difference on sleep-disordered breathing index, body mass index, heart rate in sleep, the percentage of the recording time spent with arterial oxygen saturation（SIT90） , the nocturnal mean arterial oxygen saturation and the minimal arterial oxygen saturation between COPD outpatients and inpatients clinics. Conclusion Sleep-disordered breathing can affect and aggravate patients condition of COPD.