目的探讨育龄妇女人群多囊卵巢综合征(PCOS)患者发病的相关危险因素,为临床早诊断、早治疗P—COS提供依据。方法采用病例对照的研究方法,选择285例确诊的PCOS病例作为病例组,同时选择580例非PCOS妇科患者为对照组,采用问卷调查方法来收集相关危险因素,再采用单因素、多因素分析方法来筛选PCOS发病的相关危险因素。结果多因素分析结果显示月经周期紊乱(OR=5.824)、不良心情(OR=2.852)、家族糖尿病史(OR=7.008)、家族不孕史(OR=11.953)、母亲月经不规律(OR=2.557)、缺乏体育锻炼(伽=1.866)等因素均为PCOS发病的危险因素。结论针对存在月经周期紊乱、有家族糖尿病史、有夹住不孕史、母亲月经不规律、经常心情不良、缺乏体育锻炼等高危因素女性人群,应尽早筛查、早诊断、早治疗,降低PCOS的发病率,改善PCOS预后。
Objective To explore the correlated risk factors of polycystic ovarian syndrome (PCOS) of fertile women, provide basis for early diagnosing and treating PCOS. Methods With case-control study method, we collected 285 cases of PCOS patients as case group and 580 cases of non-PCOS of gynecology patients as control group, adopted questionnaire to collect the correlated risk factors of PCOS, and then with single factor and multiple factors analysis methods screened the risk factors of PCOS. Results Multiple factors analysis result showed that the risk factors of PCOS included menstrual cycle disorder ( OR = 5. 824), bad mood ( OR=2.852), family history of diabetes ( OR=7. 008), family history of infertility i OR= 11. 953), menses irregularity of mother ( OR = 2. 557) and lack of physical exercise ( OR = 1. 866). Conclusion To aim directly at the high risk factors of female population with menstrual cycle disorder, family history of diabetes, family history of infertility, family history of diabetes, bad mood and lack of physical exercise, we should early screen, diagnose and treat POCS, in order to reduce the inci- dence rate of PCOS, and improve prognosis of PCOS.