中文摘要：

MicroRNA (miRNA ) 调停了在翻译水平的基因 silencing 为众多的生物过程导致了新奇发现。最近，在那里一直在增加证据显示 miRNAs 涉及正常有免疫力的功能和发炎。在这评论，我们在 B 房间开发，区别， apoptosis 和功能在阐明了的最近的进展上集中 miRNAs 的角色。当在控制并且维持 B 房间命运的 miRNAs 的规章的机制大部分仍然是 uncharacterized 时，在 miRNAs 和他们的目标愿望增加上推进研究我们 B 房间开发和功能的理解。如此的研究也许能为治疗自体免疫的疾病提供新治疗学的策略。

英文摘要：

MicroRNA （miRNA）-mediated gene silencing at the translational level has led to novel discoveries for numerous biological processes. Recently, there has been increasing evidence to indicate that miRNAs are involved in normal immune functions and inflammation. In this review, we focus on recent advances that have elucidated the role of miRNAs in B-cell development, differentiation, apoptosis and function. While the regulatory mechanisms of miRNAs in controlling and maintaining B-cell fate remain largely uncharacterized, further studies on miRNAs and their targets will increase our understanding of B-cell development and function. Such studies may be able to provide new therapeutic strategies for treating autoimmune diseases.