中文摘要：

在硝酸催化作用下,利用亚硒酸钠对枸杞多糖进行分子修饰,合成硒化枸杞多糖,反应条件为硝酸体积分数0.5%,70℃反应10h,透析24h。采用体外抗肿瘤实验测定硒化枸杞多糖对人宫颈癌细胞生长的抑制作用。结果显示硒化枸杞多糖对人宫颈癌细胞具有一定的抑制作用,与未硒化的枸杞多糖相比有显著性差异,且呈一定的剂量依赖性。

英文摘要：

Lycium barbarum polysaccharides were modified by sodium selenite in the presence of nitric acid as catalyst.The optimal reaction condition was the reaction at 70 ℃ for 10 h with the following dialysis for 24 h.The anticancer activity of selenited Lycium barbarum polysaccharides was evaluated in vitro.Results indicated that selenited Lycium barbarum polysaccharides could inhibit human cervical carcinoma cells,and exhibited a significant difference from Lycium barbarum polysaccharides.