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甲状腺良性病变的^18氟-脱氧葡萄糖PET／CT表现探讨

ISSN号：1006-9011
期刊名称：《医学影像学杂志》
时间：0
分类：R581[医药卫生—内分泌;医药卫生—临床医学;医药卫生—内科学] R817.4[医药卫生—影像医学与核医学;医药卫生—放射医学;医药卫生—临床医学]
作者机构：[1]南京军区南京总医院南京大学医学院临床学院核医学科,江苏南京210002, [2]南京军区南京总医院南京大学医学院临床学院医学影像科,江苏南京210002
相关基金：国家自然科学基金重大国际(地区)合作研究项目(项目批准号:81120108013,依托项目编号:30670600);江苏省自然科学基金(编号:BK2011665);南京军区南京总医院立项课题(编号:2011024)

作者：吴江[1], 朱虹[1], 王新刚[1], 桂一[1], 刘伟彦[1], 卢光明[2]

关键词：甲状腺, 18氟-脱氧葡萄糖, 正电子发射体层摄影, 体层摄影术, X线计算机, Thyroid, ^18F fluorodexyoxyglucose, Positron emission tomography

中文摘要：

目的探讨甲状腺良性病变的^18氟脱氧葡萄糖（^18F—fluorodexyoxyglucose，^18FFDG）PET／CT表现，以提高对该病变PET／CT影像的认识。方法回顾性分析经手术病理明确诊断的24例甲状腺良性病变的”FFDGPET／CT影像学资料，包括结节性甲状腺肿13例、甲状腺腺瘤10例、甲状腺局限性增生2例、桥本氏甲状腺炎4例、慢性甲状腺炎1例、亚急性甲状腺炎1例，其中10例患者甲状腺存在两个或多个病变。结果结节性甲状腺肿的异常PET／CT征象包括①甲状腺低密度结节或密度弥漫性减低；②甲状腺肿大；③钙化；④甲状腺局灶性或弥漫性FDG代谢增高。13例结节性甲状腺肿4例未见PET／CT异常征象，仅2例FDG代谢增高（局灶性、弥漫性）。甲状腺腺瘤的PET／CT异常征象包括①甲状腺低密度或略低密度结节；②囊变；③钙化；④甲状腺局灶性FDG代埘增高。10例甲状腺腺瘤仅2例局灶性FDG代谢增高。甲状腺局限性增生的PET／CT异常征象包括①甲状腺低密度结节；②甲状腺局灶性FDG代谢增高。2例甲状腺局限性增生1例局灶性FDG代谢增高。桥本氏甲状腺炎的PET／CT异常征象包括①甲状腺密度弥漫性减低；②甲状腺肿大；③甲状腺弥漫性FDG代谢增高。4例桥本氏甲状腺炎2例弥漫性FDG代谢增高。亚急性甲状腺炎和慢性甲状腺炎的PET／CT异常征象包括①甲状腺片状低密度灶；②甲状腺局灶性或弥漫性FDG代谢增高。结论甲状腺良性病变可出现FDG摄取增高，但在结节性甲状腺肿、甲状腺腺瘤、甲状腺局限性增生出现比例低，而在桥本氏甲状腺炎等炎性病变比例相对较高；甲状腺弥漫性FDG摄取多提示良性病变，而局灶性FDG摄取需作进一步的鉴别。

英文摘要：

Objective This study was designed to investigat the performance of positron emission tomography/computer tomography （PET/CT） with ^18F fluorodexyoxyglucose （is F-FDG） for benign thyroid disease. Methods PET/CT findings in 24 patients （12 M/12F; age 28～84; mean age 55. 6 years） with pathologically proved benign thyroid disease by surgery were analyzed retrospectively. Of the 24 patients, two or more benign lesions of thyroid were detected in 10 pa-tients. So 13 cases of nodular goiter, 10 cases of thyroid adenoma, 2 cases of thyroid local hyperplasia, 4 cases of Hashimoto＇s thyroiditis, one case of chronic thyroiditis and one case of subacute thyroiditis were included in the study. ResultsThe abnormal PET/CT findings of nodular goiter were listed as follows：①low-density nodule or diffuse low density in the thyroid; ② enlarged thyroid; ③ calcification; ④ focal or diffuse FDG uptake in the thyroid. Of the 13 cases of nodulargoiter, 4 cases did not show the abnormal PET/CT findings and only 2 cases showed increased FDG uptake. The abnormal PET/CT findings of thyroid adenoma were listed as follows： ① low-density nodule or a little low-density nodule; ② cysticchange; ③ calcification; ④ focal FDG uptake in the thyroid. Of the 10 cases of thyroid adenoma, only 2 cases revealed increased FDG uptake. The abnormal PET/CT findings of thyroid local hyperplasia were listed as follows： ① low-densitynodule; ② focal FDG uptake in the thyroid. Of the 2 cases of thyroid local hyperplasia, one case showed increased focal FDG uptake. The abnormal PET/CT findings of Hashimoto＇s thyroiditis were listed as follows： ① diffuse low density inthe thyroid; ② enlarged thyroid; ③ diffuse FDG uptake in the thyroid. Of the 4 cases of Hashimoto＇s thyroiditis, 2 cases revealed diffuse FDG uptake in the thyroid. The abnormal PET/CT findings of chronic thyroiditis and subacute thyroiditiswere listed as follows： ① hypodensity patch in the thyroid; ② focal or diffuse FDG uptake in the thyroid

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