中文摘要：

目的：对基本药物制度实施前后山东省社区卫生服务中心门诊处方合理用药情况进行分析。方法：比较基本药物制度实施前后社区卫生服务中心门诊处方合理用药变化情况,运用RSR法以及聚类分析法,以WHO推荐值为标准值综合评价山东省不同地区10所社区卫生服务中心处方合理用药情况。结果：基本药物制度实施后,处方药品种数均值由2.95降为2.51,书写清晰率由67.2%升至89.0%,但抗菌药物处方率由28.9%上升为41.0%,注射剂处方率由30.0%上升为43.0%,聚类分析中,＂较好＂及以上的社区卫生服务中心所占比例为60%。结论：基本药物制度实施后,山东省社区卫生服务中心处方用药总体较好,但仍存在抗菌药物及注射剂滥用等现象,应加强用药监管力度,进一步规范处方行为。

英文摘要：

Objective To analyze the status of rational drug use of outpatient prescription in community health service centers of Shandong Province before and after the implementation of essential pharmaceuticals system. Methods The status of rational drug use of outpatient prescription in community health service centers before and after the implementation of essential pharmaceuticals system was comparatively studied with RSR and cluster analysis. Results After the implementation of essential pharmaceuticals system,the average amount of prescription drugs reduced from 2. 95 to 2. 51,and the proportion of prescriptions written clearly increased from 67. 2% to 89. 0%. However,the percentage of？ prescriptions containing antibiotics increased from 28. 9% to 41.0%,and percentage of prescriptions containing injections increased from 30. 0% to 43. 0%. The result of cluster analysis showed that 60% of the community health service centers were ＂better＂. Conclusion The status of rational drug use of community health service centers in Shandong province was well after the implementation of essential pharmaceuticals system. But some problems such as abuse of antibiotics and injections still exist,which needs to be further regulated and supervised.