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基于文本挖掘技术的高血压病中成药与西药用药规律分析
  • ISSN号:1673-1727
  • 期刊名称:中华中医药杂志
  • 时间:0
  • 页码:60-63
  • 分类:R22[医药卫生—中医基础理论;医药卫生—中医学]
  • 作者机构:[1]中国中医科学院中医临床基础医学研究所,北京100700, [2]香港浸会大学中医药学院,香港
  • 相关基金:科技部重大新药创制项目(No.2013ZX09301307);国家杰出青年科学基金项目(No.30825047);国家自然科学基金青年基金项目(No.81403209);中央级公益性科研院所基本科研业务费资助项目(No.ZZ070823);中国中医科学院中医临床基础医学研究所自主选题项目(No.Z0412)
  • 相关项目:中西医结合基础-疾病证候分类研究
中文摘要:

目的:通过分析《临证指南医案》治疗痹证的用药规律,探讨温病学派代表人物叶天士治疗痹证的用药特色。方法:选取《临证指南医案》治疗痹证的医案复方,建立数据表,对药物的使用频数、功效、性味、归经、科属等特征进行统计。结果:在治疗痹证的80首汤剂复方中,药物120味,用药次数是560总频次,平均每方用药7味,方简力专。其中防己、桂枝、茯苓、白术、当归等17味药累积使用频次占总频次的52.2%,是高频常用药物。另外,蚕沙配防己、石膏配防己、独活配白术、独活配茯苓等药对也是高频常用药对。120味药物按功效划分,使用频率较高依次为:补虚药25.4%,祛风湿药16.4%,利水渗湿药12.9%;按药性划分,使用频率较高依次为:温性药46.44%,寒性药28.04%,平性药19.64%;按药味划分,使用频次较高依次为:甘味药39.51%,苦味药28.72%,辛味药18.12%;按归经划分,使用频次较高依次为:肺经17.52%,脾经17.36%,肝经15.84%,肾经12.49%;120味中药分属59种科属,使用频次较高的依次为:伞形科10.2%,豆科9.8%,多孔菌科6.1%。结论:叶天士治疗痹证用药特色寒温并用,补泻同施,气血同治,重用甘味补益气血、缓急止痛,辛开苦降宣通三焦脏腑气机,促进肢体关节经络气血流通而痹痛除。高频常用药物及药对是特色用药,为临床医生用药提供参考依据。

英文摘要:

Objective:To investigate features of YE Tian-shi in applying traditional Chinese medicine(TCM) in treatment of bi disease by analyzing the regularity of applying TCM in treatment of bi disease in A Guide to Clinical Practice with Medical Record.Methods:The compound prescriptions for bi disease recorded in A Guide to Clinical Practice with Medical Record were selected,and the data sheet was established,in order to analyze the frequency of drug usage,functions,nature and flavor,channel tropism,family and genus of drugs.Results:Eighty compound prescriptions for bi disease were selected including120 drugs with 7 drugs in every prescription.The total frequency of drug usage was 560.The accumulated usage frequency of17 commonly used traditional Chinese medicines such as fangchi root,cassia twig,Indian bread,largehead atractylodes rhizome,Chinese angelica accounted for 52.2%.The commonly used medicine suits were silkworm droppings combined with fangchi root,gypsum combined with fangchi root,doubleteeth pubescent angelica root combined with largehead atractylodes rhizome,and doubleteeth pubescent angelica root combined with Indian bread.The categories of drugs used commonly were,in order,drugs for restoring vital energy(25.4%),drugs for rheumatism(16.4%),and drugs for removing dampness and promoting dieresis(12.9%).The four natures of drugs used commonly were,in order,warm drugs(46.44%),cold drugs(28.04%),and calm drugs(19.64%).The five flavours of drugs used commonly were,in order,sweet drugs(39.51%),bitter drugs(28.72%),and pungent drugs(18.12%).The channel tropism of drugs used commonly were,in order,lung channel(17.52%),spleen channel(17.36%),liver channel(15.84%),and kidney channel(12.49%).The 120 traditional Chinese medicines belonged to 59 family and genus,which used commonly were,in order,umbeliferae(10.2%),leguminosae(9.8%),and polyporeceae(6.1%).Conclusion:The features of YE Tian-shi in treating bi disease were cooling and warming in co

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期刊信息
  • 《中华中医药杂志》
  • 中国科技核心期刊
  • 主管单位:中国科学技术协会
  • 主办单位:中国中医药学会
  • 主编:佘倩
  • 地址:北京市和平街北口樱花路甲4号
  • 邮编:100029
  • 邮箱:
  • 电话:
  • 国际标准刊号:ISSN:1673-1727
  • 国内统一刊号:ISSN:11-5334/R
  • 邮发代号:18-90
  • 获奖情况:
  • 国家中医药管理局优秀期刊一等奖
  • 国内外数据库收录:
  • 美国化学文摘(网络版),英国农业与生物科学研究中心文摘,波兰哥白尼索引,美国剑桥科学文摘,日本日本科学技术振兴机构数据库,中国中国科技核心期刊,中国北大核心期刊(2008版),中国北大核心期刊(2011版),中国北大核心期刊(2014版)
  • 被引量:36061