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红绒毛羊蹄甲中的二氢黄酮醇苷和黄烷醇类成分
  • ISSN号：1001-5302
  • 期刊名称：《中国中药杂志》
  • 时间：0
  • 分类：R284.1[医药卫生—中药学;医药卫生—中医学]
  • 作者机构：[1]中国医学科学院中国协和医科大学药物研究所中草药物质基础与资源利用教育部重点实验室,北京100050, [2]北京联合大学应用文理学院生物活性物质与功能食品北京市重点实验室,北京100083
  • 相关基金：国家自然科学基金项目（20432030）;新世纪优秀人才支持计划（NCET）
作者： 尚小雅[1,2], 李帅[1], 王映红[1], 王素娟[1], 杨永春[1], 石建功[1]
关键词： 豆科, 红绒毛羊蹄甲, 二氢黄酮醇苷, 黄烷-3-醇, Legunfinosae, Bauhinia aurea, dihydroflavonol glycosides, flavan-3-ols
中文摘要：

目的：研究红绒毛羊蹄甲Bauhinia aurea的化学成分。方法：应用各种色谱技术进行分离纯化,用MS和NMR分析确定化合物结构。结果：从红绒毛羊蹄甲90%乙醇提取物的醋酸乙酯萃取部位中分离得到8个化合物,分别鉴定为异黄杞苷（1）、落新妇苷（2）、新落新妇苷（3）、异落新妇苷（4）、新异落新妇苷（5）、（2R,3S）-儿茶精6）、（2R,3R）-表儿茶精（7）和（2R,3R）-3-O-没食子酰表儿茶精（8）。结论：除化合物2,6和8外,其余5个化合物均属首次从该属植物中发现。

英文摘要：

Objective： To study the chemical constituents ofBauhinia aurea. Method： The compounds were isolated by column chromatography over silica gel, reversed-phase RP-18, and Sephadex LH -20. MS and NMR spectroscopic methods were used to determine structures of purified compounds. Result： Eight compounds were isolated from the ethyl acetate soluble fraction of the ethanolic extract and their structures were elucidated as isoengeletin （1）, astilbin （2）, neoastilbin （3）, isoastilbin （4）, neoisoastilbin （5）, （ ＋ ）-catechin （6）, （ - ）-epicatechin （7） and （ - ）-epicatechin 3-O-gallate （8）. Conclusion： Five compounds were isolated from this genus for the first time except for 2, 6 and 8.

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期刊信息
  • 《中国中药杂志》
  • 北大核心期刊（2011版）
  • 主管单位:中国科学技术协会
  • 主办单位:中国药学会
  • 主编：肖培根
  • 地址：北京市东直门内南小街16号
  • 邮编：100700
  • 邮箱：cjcmm2006@126.com
  • 电话：010-64087589
  • 国际标准刊号：ISSN：1001-5302
  • 国内统一刊号：ISSN：11-2272/R
  • 邮发代号:2-45
  • 获奖情况:
  • 国内外数据库收录:
  • 美国国际药学文摘,美国化学文摘（网络版）,英国农业与生物科学研究中心文摘,波兰哥白尼索引,荷兰文摘与引文数据库,荷兰医学文摘,美国生物医学检索系统,美国生物科学数据库,日本日本科学技术振兴机构数据库,中国中国科技核心期刊,中国北大核心期刊（2004版）,中国北大核心期刊（2008版）,中国北大核心期刊（2011版）,中国北大核心期刊（2014版）,英国英国皇家化学学会文摘,中国北大核心期刊（2000版）
  • 被引量:94720