目的探讨自体喙突移植重建下颌髁突对下颌骨生长发育的影响。方法18只幼年雄性山羊随机分成A(n=10)和B(n=8)两组,所有动物均手术切除右侧髁突,取同侧喙突移植重建下颌髁突。术后48周时处死所有A组动物,对下颌骨及重建髁突形态进行大体观察与测量。术后24和48周各处死B组4只实验动物进行组织学检查,左侧下颌骨作为正常对照组。结果术后48周时双侧升支高度、下颌骨高度以及下颌骨长度无明显差异,手术侧重建髁突明显增大,同时升支宽度较正常侧缩小;重建髁突表面有再生的关节软骨,其组织学结构与正常关节软骨类似。结论自体喙突移植重建髁突未对下颌骨生长发育产生明显影响,其中功能刺激是促进下颌骨继续生长发育的主要原因。
Objective To study the growth of the mandible after condylar reconstruction by autogenous coronoid process graft. Methods Eighteen growing male goats were included in this study and divied into group A (n = 10) and B (n = 8 ). Each animal underwent right condyle removal and was treated by coronoid process graft. Three-dimensional computerised tomography was performed at different time intervals. Animals in group A were sacrificed at 48 weeks after operation for the measurement of mandibular growth. Four animals in group B were killed at 24 and 48 weeks after operation for histological examination. Results No difference was found in ramus height, mandibular height, and mandibular length between the two sides at 48 weeks postoperatively. The reconstructed condylar size increased significantly, whereas there was a significant reduction of ramus width on the operated side. A well-organised fibrocartilage was seen at the neocondylar surface over time. Conclusion The reconstructed condyle by autogenous coronoid process has the potential to grow under functional stimuli. Therefore, this technique may serve as an alternative method for condylar reconstruction in growing individuals.