中文摘要：

以二氯甲烷为溶剂,1,4-二氮杂二环[2.2.2]辛烷为催化剂,取代靛红,芝麻酚和丙二腈经三组分Michael-环化反应合成了16个新型的芝麻酚并吡喃螺环氧化吲哚拼接衍生物——6-胺基-5＇-取代基-1＇-取代基-2＇-氧-7＇-取代基螺环[1,3]-二氧亚甲基-[4,5-并]-苯并吡喃-8,3＇-吲哚基]-7-腈,产率85%~96%,其结构经1H NMR,13C NMR和HR-ESI-MS表征。讨论了底物上的取代基对反应速度和产率的影响。

英文摘要：

Sixteen novel spiro-fused pyranyl benzo [ d] [ 1,3 ] dioxol oxindole derivatives, 6-amino-1 ＇- substituting group-2＇-oxospiro { [ 1,3 ] dioxolo [ 4,5-g ] chromene-8,3 ＇-indoline } -7-carbonitrile, were synthesized in yield of 85% - 96% by tandem Michael-cyclization reaction of sesamol, malononitrile and substituted isatins, using methylene chloride as the solvent, 1,4-diazabicyclo [ 2.2. ：2 ] octane as the catalyst, at room temperature. The structures were characterized by 1H NMR, 13C NMR and HRESI-MS. Relationship of reaction speed, yields and substituent groups in reactions were investigated.