在这份报纸,我们在在没有规模的 neuronal 网络堵住的信息传播延期和离子隧道上在依赖调查空间与时间的模式和同步转变的进化。作为 neuronal 动力学的内在的模型,我们使用合并隧道堵住和内在的噪音的 Hodgkin 贺胥黎方程。延期在塑造 neuronal 网络的动力学起一个重要还微妙的作用,这被显示出。特别地,当延期增加,与同步转变有关的不规则、常规的宣传有刺激性的前面的区域间歇地出现。而且,工作的钠的部分和钾离子隧道罐头也在 neuronal 网络的空间与时间的动力学上有重要影响。当堵住的钠隧道的部分增加,有刺激性的事件的频率减少,它接着作为然而,由于大振幅的刺激的虚拟缺席是不正常的 neuronal synchrony 的增加表明。Expectedly,我们也证明不管堵住的信息传动延期和隧道,更大的联合力量改进同步。介绍结果对网络尺寸的变化也是柔韧的,因此提供能便于离子隧道在 neuronal 的空间与时间的动力学上堵住和信息传播延期的联合影响的理解的卓见联网。
In this paper,we investigate the evolution of spatiotemporal patterns and synchronization transitions in dependence on the information transmission delay and ion channel blocking in scale-free neuronal networks.As the underlying model of neuronal dynamics,we use the Hodgkin-Huxley equations incorporating channel blocking and intrinsic noise.It is shown that delays play a significant yet subtle role in shaping the dynamics of neuronal networks.In particular,regions of irregular and regular propagating excitatory fronts related to the synchronization transitions appear intermittently as the delay increases.Moreover,the fraction of working sodium and potassium ion channels can also have a significant impact on the spatiotemporal dynamics of neuronal networks.As the fraction of blocked sodium channels increases,the frequency of excitatory events decreases,which in turn manifests as an increase in the neuronal synchrony that,however,is dysfunctional due to the virtual absence of large-amplitude excitations.Expectedly,we also show that larger coupling strengths improve synchronization irrespective of the information transmission delay and channel blocking.The presented results are also robust against the variation of the network size,thus providing insights that could facilitate understanding of the joint impact of ion channel blocking and information transmission delay on the spatiotemporal dynamics of neuronal networks.