在昆虫中,RNAi是一种对抗外源病毒的天然免疫方式,基于生物体中的这种内在机制而建立的RNAi技术已经被广泛用来研究多种昆虫基因的功能。近年的研究结果表明RNAi技术在抵御害虫和防治益虫疾病方面具有潜在的应用价值,有可能对农业有害生物的控制起到巨大的推动作用。本文综述了RNAi与昆虫免疫、及其在昆虫基因功能研究、害虫控制、益虫疾病控制和昆虫系统生物学方面的最新研究进展,并展望了RNAi在昆虫学研究中的发展趋势。
RNAi has been recognized as an innate immune mechanism against extracellular viruses,based on this biological mechanism,RNAi technology has been established in insects and used widely to investigate kinds of insects' gene functions.In the past years,researchers have found that RNAi has a potential use against insect pests and control beneficial insects' disease,and which may will provide a huge boost for agricultural pest control.We reviewed recent advances focusing on RNAi and insect immunology,as well as its use in gene function study,insect pest control,beneficial insects' disease control along with the insect system biology,we also prospect the future development of RNAi applied in entomology.