目的早产儿脑损伤是造成早产儿死亡及伤残的重要原因,也是近年国内的研究重点,但目前仍缺乏对全国早产儿脑损伤领域研究现状的全面分析和评估。本研究将首次利用共词分析方法对国内近十年发表于国内期刊的该领域文献进行分析,深度剖析我国早产儿脑损伤的研究状况及进展,为进一步研究奠定基础。方法于2013年4月在中国知网以“早产儿”、“脑损伤”为自由词,限定期刊年限为2003年1月至2012年12月,进行文献检索,提取所有相关文献,排除不符合研究目的的文献,纳入符合研究标准的文献,再用Excel2007进行关键词的统计和分析,利用Ucinet6.0及Netdraw描绘共现分析图,将关键词之间的共篇关系可视化。结果共纳入文献173篇,提取高频关键词28个,成功呈现了国内此领域目前的研究热点,通过共词分析得出各个高频关键词之间的疏密关系,展现了各研究热点之间的内在联系。结论目前国内早产儿脑损伤领域的研究集中于脑室周围白质软化、颅内出血、缺氧缺血性脑病等疾病,对于早产儿脑损伤的病理机制、诊断、预防和治疗的研究也有较多涉猎。
Objective Brain injury is a major cause of premature infant mortality and disability, which has become a priority research topic in our country. However, comprehensive assessment and analysis on current research status in this field are scarce. In this study, we used co-word analysis method to analyze all the research papers on brain injury in the premature infants published in the Chinese journals during last decade, in the hope to formulate foundation for further study. Methods We retrieved all the papers in Chinese National Knowledge Infrastructure (CNKI) from 2003.1 to 2012. 12, using keywords "premature infants" and "brain injury". Microsoft Office Excel 2007, Ucinet 6.0 and Netdraw were used to analyze the data and generate diagrammatic representation. Results Total of 173 articles were identified and 28 frequently used keywords were extracted. The co-word relationship of these frequently used keywords and research focus were successfully revealed. Conclusions Nowadays, researches on brain injury in the premature infants are focused on periventricular leukomalacia (PYL) , cerebral hemorrhage and hypoxic-ischemic encephalopathy (HIE). ranging from pathological mechanisms, diagnosis, prevention to treatment.