中文摘要：

以脱氢枞胺和苯甲酰氯为原料，合成了N-苯甲酰基-脱氢枞胺。通过B环氧化，得到N-苯甲酰基-脱氢枞胺-7-酮，用IR、MS和1HNMR光谱确证其结构。对N-苯甲酰基-脱氢枞胺-7-酮进行了雄激素受体（AR）结合活力测试。结果表明，N-苯甲酰基-脱氢枞胺-7-酮与AR具有一定的结合活性，半数抑制浓度（IC50）为83．8nmol／L。

英文摘要：

N-benzoyl-dehydroabietylamine was synthesized from dehydroabietylamine and benzoyl chloride. Then N-benzoyldehydroabietylamine-7-one was synthesized from the former by oxidizing at ring-B. Their structures were characterized by IR, MS and 1H NMR spectroscopies. The androgen receptor（AR） binding activities of N-benzoyl-dehydroabietylamine-7-one was tested. It has been found that N-benzoyl-dehydroabietylamine-7-one presents certain androgen receptor binding activity with IC50 value of 83.8 nmol/L.