自由探索实验作为国际公认的评价啮齿类动物特质焦虑情绪的方法已得到广泛应用,但国内鲜有介绍与报道.特质焦虑并不是每时每刻都在变化的,因此任何一个用来评估它的模型都需要在连续的实验中给出相同的结果.出于这点考虑,必须探讨自由探索实验作为大鼠特质焦虑评价方法的重测信度.该文简要回顾了自由探索实验的一般原理、实验过程及面临的问题,以期对啮齿类动物状态情绪与特制情绪相关工作的开展进行必要的理论铺垫.
The free exploratory paradigm (FEP)has been widely applied as an internationally recognized model of evaluating rodents trait anxiety, but rarely introduced and reported in China. Trait anxiety doesnot vary from moment to moment, therefore any model used to evaluate it needs to give the same results in sequential trials. With this in mind, the test-retest reliability of the FEP in rats must be evaluated. Here reviews the general principle, experiment process and problems of FEP to establish necessary theoretical framework for the following study of rodents' state and trait emotion.