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Supramolecular Wireframe DNA Polyhedra: Assembly and Applications
  • ISSN号:1001-604X
  • 期刊名称:《中国化学:英文版》
  • 时间:0
  • 分类:TP317[自动化与计算机技术—计算机软件与理论;自动化与计算机技术—计算机科学与技术] TB383[一般工业技术—材料科学与工程]
  • 作者机构:[1]School of Chemistry and Chemical Engineering, Hefei University of Technology, 193 Tunxi Road, Hefei, Anhui 230009, China, [2]Department of Chemistry, Purdue University West Lafayette, Indiana 47907, USA, [3]CAS Key Laboratory of Soft Matter Chemistry, School of Chemistry and Materials Science, University of Science and Technology of China, Hefei, Anhui 230026, China
  • 相关基金:This work was supported by the National Natural Science Foundation of China (Nos. 21273214, 21521001 and 21605033), the National Science Fund for Distinguished Young Scholars (No. 21425521), the National Key Research and Development Program of China (No. 2016YFA0201300), Hefei Center for Physi- cal Science and Technology (No. 2014FXCX010), the Collaborative Innovation Center of Suzhou Nano Science and Technology, the Fundamental Research Funds for the Central Universities (No. JZ2016HGPA0734), and start-up funding from Hefei University of Technology.
中文摘要:

Wireframe,用 DNA 做的多面的、超分子的建筑群有一致尺寸,定义三维的形状,多孔的方面,空内部,好 biocompatibilities,和化学 functionalizability。他们向各种各样的应用程序在自底向上的 nanoengineering 授与大潜力。在这评论,我们在合理设计和 DNA wireframe polyhedra 的规划汇编总结最近的进展。他们的集会基于三区别地不同的策略:单个基于海滨的汇编,基于瓦的集会,和 scaffolded DNA origami。在 templated nanomaterial 汇编和 in-vivo 货物交货的这些多面的结构的应用程序被讨论。以后,扩展结构的复杂性并且探索他们的应用程序,特别在 nanomaterials 科学和 biomedicines,这的一个主要焦点应该很快正在开发并且演变结构的 DNA 纳米技术的活动。

英文摘要:

Wireframe, polyhedral, supramolecular complexes made of DNA have uniform sizes, defined three-dimensional shapes, porous facets, hollow interiors, good biocompatibilities, and chemical functionalizability. They confer great potentials in bottom-up nanoengineering towards various applications. In this review, we summarize recent ad- vances in the rational design and programmed assembly of DNA wireframe polyhedra. Their assembly is based on three distinctively different strategies: individual strands-based assembly, tile-based assembly, and scaffolded DNA origami. Applications of these polyhedral structures in templated nanomaterial assembly and in-vivo cargo delivery are discussed. In the future, expanding the structural complexity and exploring their applications, especially in na- nomaterials science and biomedicines, should be a primary focus of this rapidly developing and evolving activity of structural DNA nanotechnology.

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期刊信息
  • 《中国化学:英文版》
  • 主管单位:
  • 主办单位:中国化学会
  • 主编:
  • 地址:上海市枫林路354号中科院上海有机化学研究所
  • 邮编:200032
  • 邮箱:
  • 电话:021-54925243
  • 国际标准刊号:ISSN:1001-604X
  • 国内统一刊号:ISSN:31-1547/O6
  • 邮发代号:4-646
  • 获奖情况:
  • 中国期刊方阵“双高”期刊
  • 国内外数据库收录:
  • 美国化学文摘(网络版),荷兰文摘与引文数据库,美国科学引文索引(扩展库),日本日本科学技术振兴机构数据库,英国英国皇家化学学会文摘
  • 被引量:175