Wireframe,用 DNA 做的多面的、超分子的建筑群有一致尺寸,定义三维的形状,多孔的方面,空内部,好 biocompatibilities,和化学 functionalizability。他们向各种各样的应用程序在自底向上的 nanoengineering 授与大潜力。在这评论,我们在合理设计和 DNA wireframe polyhedra 的规划汇编总结最近的进展。他们的集会基于三区别地不同的策略:单个基于海滨的汇编,基于瓦的集会,和 scaffolded DNA origami。在 templated nanomaterial 汇编和 in-vivo 货物交货的这些多面的结构的应用程序被讨论。以后,扩展结构的复杂性并且探索他们的应用程序,特别在 nanomaterials 科学和 biomedicines,这的一个主要焦点应该很快正在开发并且演变结构的 DNA 纳米技术的活动。
Wireframe, polyhedral, supramolecular complexes made of DNA have uniform sizes, defined three-dimensional shapes, porous facets, hollow interiors, good biocompatibilities, and chemical functionalizability. They confer great potentials in bottom-up nanoengineering towards various applications. In this review, we summarize recent ad- vances in the rational design and programmed assembly of DNA wireframe polyhedra. Their assembly is based on three distinctively different strategies: individual strands-based assembly, tile-based assembly, and scaffolded DNA origami. Applications of these polyhedral structures in templated nanomaterial assembly and in-vivo cargo delivery are discussed. In the future, expanding the structural complexity and exploring their applications, especially in na- nomaterials science and biomedicines, should be a primary focus of this rapidly developing and evolving activity of structural DNA nanotechnology.