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慢传输型便秘患者粪菌移植治疗的护理
  • ISSN号:1001-4152
  • 期刊名称:《护理学杂志》
  • 时间:0
  • 分类:R473.5[医药卫生—护理学;医药卫生—临床医学]
  • 作者机构:[1]同济大学附属第十人民医院肠道微生态治疗中心,上海200072, [2]中国人民解放军南京军区南京总医院普通外科肠道微生态治疗中心,上海200072
  • 相关基金:国家自然科学基金面上项目(81670493);国家消化系统疾病临床医学研究中心科技支撑项目(2015BAI13B07)
中文摘要:

目的总结30例慢传输型便秘患者行粪菌移植(FMT)治疗的护理方法。方法对30例慢传输型便秘患者行粪菌移植治疗。治疗前做好入院宣教、供体护理、受者肠道准备,配制移植菌液,经鼻肠管注入菌液,移植后密切观察不良反应并做好饮食指导。结果经粪菌移植治疗后第12周,11例(36.7%)患者获得临床治愈,18例(60.0%)获得临床改善,1例无效。患者自主排便次数从治疗前的平均1.2次/周逐渐增加,至12周达4.2次/周。治疗后不同时间点生活质量评分显著低于治疗前(P〈0.05,P〈0.01)。结论粪菌移植治疗慢传输型便秘效果良好。在粪菌移植治疗中,供体筛查的准确性、菌液提取与配制、移植前后患者适应性以及移植后肠康复中饮食、活动指导等是护理的重点。

英文摘要:

Objective To explore nursing care measures during fecal microbiota transplant(FMT) for 30 patients with slow transit constipation. Methods A total of 30 patients with slow transit constipation were treated with FMT. Before treatment, admission education was delivered to the patients, and donor care, recipientrs bowel preparation, configuration of transplanted microbial liquid were conducted. Microbial liquid was injected within 6 min through a nasoenteric tube, then adverse events were recorded and diet guidance was provided. Results At 12 weeks after FMT treatment, 11 patients(36.7 %) were clinically cured, 18 (60.0 % ) received clinical improvement, and 1 patient was irresponsive to FMT. Spontaneous defecation among these patients increased from an average of 1.2 times/week before FMT treatment to 4.2 times/week at 12 weeks. Also, patients' quality of life scores was sig- nificantly lower than before FMT treatment (P〈0.05, P〈0.01). Conclusion FMT is effective for slow transit constipation. Nur- sing care play an important role in donor screening, microbes extraction and microbial liquid preparation, patient adjustment before treatment, diet guidance after treatment, and exercise guidance, etc.

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期刊信息
  • 《护理学杂志》
  • 中国科技核心期刊
  • 主管单位:教育部
  • 主办单位:华中科技大学同济医学院
  • 主编:刘义兰
  • 地址:武汉市解放大道1095号
  • 邮编:430030
  • 邮箱:jns@tjh.tjmu.edu.cn
  • 电话:027-83662666 83663697
  • 国际标准刊号:ISSN:1001-4152
  • 国内统一刊号:ISSN:42-1154/R
  • 邮发代号:
  • 获奖情况:
  • 中国科技论文统计源期刊
  • 国内外数据库收录:
  • 中国中国科技核心期刊
  • 被引量:1204