中文摘要：

预防或者减轻心肺转流（cardiopulmonary bypass，CPB）心脏手术引起的肺损伤是心血管麻醉一个极为重要的研究领域。人工的循环、缺血，再灌注损伤以及肺塌陷后复张是造成肺部炎症反应的关键因素。急性肺损伤后应用全氟化碳进行液体通气已经被证实可以改善肺的氧合。在体外循环前、期间以及体外循环后进行液体通气（1iquid ventilation，LV），可以有效地减少中性粒细胞的浸润，减少肺内活性氧族产物，从而产生肺保护作用。

英文摘要：

Prevention or reduction of cardiopulmonary bypass-induced pulmonary injury has become critically important researching aspect of cardiovascular anesthesia. Artificial circulation, ischemia/reperfusion injury and pulmonary re-expansion after collapse are the key elements to induce pulmonary inflammatory reaction. Liquid ventilation using perfluorocarbon has been shown to improve oxygenation after acute lung injury. Liquid ventilation can effectively reduce neutrophil infiltration and reactive oxygen species production in the lungs, thus exerting protective effects against acute lung injury.