中文摘要：

通过分子内部还原关环法合成4种不同的2,5位带卤素基团的硅杂环戊二烯,尝试用这4种不同的硅杂环戊二烯反应底物通过Sonogashira偶联反应以及Negishi偶联反应制备2,5位不对称硅杂环戊二烯化合物。通过一系列反应发现2,5位带相同卤素的硅杂环戊二烯无法制备不对称硅杂环戊二烯化合物,而2,5位带不同卤素的2-氯-5-碘-1,1-二甲基-3,4-二苯基-硅杂环戊二烯是制备2,5位不对称硅杂环戊二烯化合物的最佳反应底物。部分化合物结构经过质谱或氢谱测试确认。

英文摘要：

Four kinds of siloles beard same halogens on the 2,5-positions were synthesized based on endo-endo intramolecular reductive cyclization.These siloles were used to synthesize 2,5-position asymmetrical siloles by the Sonogashira coupling reaction and the Negishi coupling reaction,however,these efforts have failed,the asymmetrical siloles were not obtained.The best method to get the asymmetrical silole is from the 2-chloro-5-iodo-1,1-dimethyl-3,4-diphenyl-silole.Some compounds were confirmed by the H1-NMR or MS.