中文摘要：

以Ⅰ型胶原分子为原料,采用盐析-丙酮脱水-戊二醛交联的反应路线制备了胶原重聚集纤维材料,并采用 SEM、FT-IR、DSC 及比表面孔隙分析仪对材料的微观形貌、热稳定性和比表面积等进行了表征.结果表明,胶原重聚集纤维材料外观为浅黄色蓬松纤维形态,微观尺度上由直径在30~150 nm 之间的纳米纤维交织而成；材料比表面积为26 m2/g,远大于天然胶原纤维及其改性产物的比表面积；材料中胶原分子的三股螺旋结构未被破坏；材料的热变性温度达到85℃.胶原重聚集纤维材料的制备思路,有望为胶原资源在吸附材料、催化剂载体以及生物材料等领域的应用提供参考.

英文摘要：

Collagen re-assembled fibers were prepared from type Ⅰ collagen molecules via salting out-acetone de-hydration-glutaraldehyde crosslinking.Then the material was characterized by scanning electron microscopy （SEM）,Fourier transform infrared spectroscopy （FT-IR）,differential scanning calorimetry （DSC）and specific surface area analyzer,to obtain its morphology,thermal stability and specific surface area.The results showed that the collagen re-assembled fibers presented a fluffy fibrous appearance.SEM images revealed that the colla-gen re-assembled fibers were composed of interwoven nano fibrils （30-150 nm in diameter）,at the micro-scale. The specific surface area of the material was 26 m2/g,which was more than that of natural and modified colla-gen fibers.Collagen molecules in the material still kept a natural triple helix structure.The thermal denatur-ation temperature of the material was 85 ℃.The preparation of collagen re-assembled fibers provides a prospect for further utilization of collagen resource,such as adsorption material,catalyst supported material and bioma-terial.