目的比较腹腔镜和开腹手术治疗胃癌合并2型糖尿病患者的临床疗效,寻求最佳的治疗方法。方法以解放军总医院2008年6月-2010年6月治疗的76例胃癌合并糖尿病患者为研究对象,对其临床资料进行回顾性分析。开腹手术组(opensurgery,OS)38例;腹腔镜手术组(laparoscopic surgery,LAP)38例。对两组手术方法及临床疗效等进行比较。结果腹腔镜手术组有效率为73.7%,开腹手术组为57.9%,差异有统计学意义(P〈0.05);在切口大小、出血量、术后肛门排气时间、进食时间及白细胞和中性粒细胞计数等数据进行比较,腹腔镜手术组均优于开腹组(P〈0.05)。结论在胃癌合并2型糖尿病患者的治疗中,腹腔镜全胃切除术较开腹手术疗效显著。
Objective To find out the best procedure for patients with gastric cancer accompanying type 2 diabetes mellitus (DM) by comparing the curative effect of laparoscopic gastrectomy and laparoscopic total gastrectomy. Methods Clinical data about 76 patients with gastric cancer accompanying DM admitted to our hospital from June 2008 to June 2010 were retrospectively analyzed. The patients were divided into laproscopic gastrectomy group (n=38) and laproscopic total gastrectomy group (n=38). The curative effect of the two procedures was compared. Results The effective rate was 73.7% and 57.9% for the laparoscopic total gastrectomy group and laparoscopic gastrectomy group, respectively (P 〈 0.05). The incision size was smaller, blood loss was less, the postoperative anal exhaust time and feeding time were shorter, the number of white blood cells and neutrophils was lower in laparoscopic total gastrectomy group than in laparoscopic gastrectomy group (P 〈 0.05). Conclusion The curative effect of laparoscopic total gastrectomy is better than that of laparoscopic gastrectomy for patients with gastric cancer accompanying type 2 DM.