目的探讨裁剪式前颞叶内侧切除术治疗颞叶内侧型癫痫的手术方法和治疗效果。方法21例顽固性颞叶癫痫患者,采用脑功能制图及神经导航等辅助,行裁剪式前颞叶内侧切除术治疗,切除前颞叶、杏仁核及海马。采用分级量表针对癫痫发作控制效果进行评价。结果术后随访6—29个月,21例患者神经功能均改善,无严重手术并发症。其中EngelI级16例(76%);EngellI级3例(14%);Engelm级2例(10%)。结论裁剪式前颞叶内侧切除术是治疗颞叶癫痫的有效方法。脑功能制图及神经导航辅助下手术切除杏仁核及海马彻底,避免了语言区和视放射的损伤。
Objective To explore the surgical skills, effects and complications of Tailored Temporal lobectomy via the anterolateral Approach for the treatment of mesial temporal lobe epilepsy (MTLE). Methods The Temporal lobeetomy via the anterolateral Approach was performed under the guidance of functional brain mapping and neuronavigation system in 21 patients with intractable MTLE. All the patients were followed up from 6 to 29 months after surgeries. Results In 21 patients , 16 patients (76%) ,3 patients( 14% ) and 2 patients( 10% ) belonged in Engel grade I ( seizure - free) , grade II ( rare seizures) and grade III ( worthwhile improvement) , respectively. Neuro - functions were improved after the surgeries in 16 patients. No severe complications occurred in all the patients. Conclusions The Temporal lobeetomy via the anterolateral Approach under the guidance of functional brain mapping and neuronavigation system is an effective method of treating intractable MTLE because the volume of medial hippocampus and amygdala removal is extremely variable . It also provides a protective way of the optic radiation and language area.