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中文摘要：
肺癌是预后极差的恶性肿瘤之一，已经上升到肿瘤死亡原因的首位，成为严重威胁人类健康的恶性肿瘤。肺癌的早期治疗除了手术、放疗和化疗外，生物治疗已经成为重要的辅助手段。海参多糖具有多种生物活性，它是从海参体内提取的一种糖胺聚糖，具有良好的抗凝血和抗血栓作用。研究显示其具有抗肿瘤活性及细胞免疫调节功能，通过抑制肿瘤新生血管的形成和抗凝血来实现抗肿瘤作用，通过激活T细胞调节机体细胞免疫功能。本文就海参多糖在抗肺癌活性及T细胞免疫功能调节方面的基础研究进展进行综述。
英文摘要：
The lung cancer is one of very poor malignant tumors in prognosis. It has reached the top of cause of death and become to threaten the health of human in malignant tumor. The biotherapy has become the important adjunctive therapy method for pulmonary cancer, apart from surgery, chemotherapy and radiotherapy. The polysaccharide which was selectived from sea cucumber has more important biologic activity substance. It has satisfactory effects in anticoagulated blood and anti-thrombosis as biotherapy, and it has the function of cyto-immunity and anti-neoplastic activity. The activity was carried out by inhibiting the form of neovascular of tumor and anti-coagulated blood. It reinforces the cellular immune function by activating T cells. So, we reviewed the progression of grounding research in anti-lung tumor activity and the regulation of T cellular immune function for polysaccharide from sea cucumber.
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