中文摘要：

目的观察眼外肌本体感受器破坏术治疗无中间带型先天性眼球震颤（CN）的疗效。方法选取2015年4月至2016年8月在北京大学人民医院眼科住院治疗的15例无中间带型CN患者的临床资料。全部患者术前均采用国际标准视力表检查最佳矫正视力；采用MG6B-5手持式放大镜确定眼球震颤类型；采用YZ6F型检眼镜检查眼底；采用YZ5裂隙灯显微镜检查眼前节；采用RM8900电脑验光仪进行验光；采用L-2510同视机检查双眼视功能；并检查患者的头位、眼位及注视性质。全部患者术后1个月检查最佳矫正视力。对无中间带型CN患者施行跟外肌本体感受器破坏术。手术采怖破坏双眼4条水平直肌肌肉本体感受器的方式。年龄和视力的描述以均数±标准差（x±s）表示。采用配对t检验的方法对患者术前与术后的最佳矫正视力进行比较。结果全部患者术后眼位均为正位，无异常头位，且眼球各方向转动均不受限。在15例无中间带型CN患者中，有6例患者右眼最佳矫正视力在术后1个月时提高≥2行，9例患者右眼视力稳定。仅有4例患者左眼最佳矫正视力在术后1个月时提高≥2行，11例患者左眼视力稳定。术后与术前的右眼最佳矫正视力分别为0．319±0．28和0．29±0．23，术后视力提高，经比较差异有统计学意义（t=3．35，P〈0．05）。术后与术前的左恨最佳矫正视力分别为0．37±0．28和0．29±0．23，术后视力提高，经比较差异有统计学意义（t=3．04，p〈0．05）。结论眼外肌本体感受器破坏术是治疗无中间带型CN的有效手术方式。

英文摘要：

Objective To observe the efficacy of the destruction of extraocular muscle proprioception in the treatment of congenital nystagmus （CN） without intermediate band. Methods The clinical data of fifteen patients with CN without intermediate band in Peking University People＇s Hospital from April 2015 to August 2016 were selected. All of the patients before surgery were given best corrected visual acuity. All patients were given best corrected visual acuity at one months postoperatively. Preliminary determination of nystagmus types by MG6B-5 handheld magnifier, examination of ocular fundus by YZ6F type ophthalmoscope, examination the anterior segment by YZ5 slit lamp microscopy, examination of an optician by RM8900 computer optometry, examination of binocular visual function by L-2510 identical vision machine. And check the head position, eye position and fixation. Destruction of extraocular muscle proprioception in patients with CN without intermediate band. The operation with eyes four horizontal rectus muscle proprioceptors failure mode.Age and visual expression to mean±standard deviation with （x±s）. Using the paired t-test to compare the preoperative and postoperative visual acuity. Results After the operation, all patients with postoperative eye are positive, and no abnormal head position. Eye movement in each direction are not limited. In fifteen cases with no intermediate type CN patients, six cases of patients with best corrected visual acuity at one months after surgery increased more than two lines, nine cases of patients with visual acuity stable. Only four cases of best corrected visual acuity at one months after surgery increased more than two lines, eleven cases of patients with stable visual acuity. The right best corrected visual acuity after operation was 0.39 ± 0.28 and 0.29 ± 0.23 respectively, and the visual acuity was improved after operation. The difference was statistically significant （t= 3.35, P〈0.05）. The best corrected visual acuity of left eye after operation was 0.37 ±