中文摘要：

目的：评价健脾消脂方联合运动饮食疗法治疗非酒精性脂肪性肝炎（NASH）的临床疗效。方法：60例NASH患者按照随机双盲对照设计方法,分为治疗组和对照组各30例。治疗组患者给予健脾消脂方（0.5剂/次,2次/d,口服）联合运动饮食治疗。对照组患者给予易善复（456 mg/次,3次/d,口服）联合运动饮食治疗。疗程均为24周。观察两组患者治疗前后BMI值、肝功能（ALT、AST、GGT）、血脂（TC、TG）、肝/脾CT比值和中医证候积分变化。结果：治疗24周后,治疗组患者BMI、肝功能（ALT、AST、GGT）、血脂（TC、TG）较治疗前明显下降（〈0.05）,与对照组相比差异有显著性意义（〈0.05）;治疗组患者中医证候积分较对照组有明显改善（〈0.05）;治疗组患者肝/脾CT比值较治疗前升高了0.22±0.20,对照组患者升高了0.07±0.18;治疗组肝/脾CT比值较对照组明显改善（〈0.05）。结论：健脾消脂方联合运动饮食疗法能明显改善非酒精性脂肪性肝炎患者的临床症状、肝功能、血脂水平和肝/脾CT比值,具有较好的临床疗效,有一定推广应用价值。

英文摘要：

Objective：To observe the clinical effect of strengthening spleen and excerting dampness decoction in the treatment of non-alcoholic fatty live（rNAFLD）. Methods：Total of 60 patients with NAFLD were randomly divided into the treatment group（n = 30）and the control group（n=30）,the patients in the treatment group were treated with strengthening spleen and excerting dampness decoction,and the patients in the control group（n = 30）were treated with polyene phosphatidylcholine capsules,respectively for consecutive 24 weeks. The BMI score,the levels of serum ALT,AST,GGT,TC and TG,liver / spleen CT value ratio and the Chinese medicine symptom scores were detected before and after treatment,respectively. The measurement data between two groups were compared using t test,and the count data were compared using2 test. Results：After treatment,the BMI score between treatment group and control group had significant difference（ 〈0.05）. The liver function（ALT,AST,GGT）and blood lipid（TC,TG）of the two groups were improved when compared with before treatment（ 〈0.05）.The Chinese medicine symptom scores in the treatment group improved more obviously than that in the control group（ 〈0.05）. The liver / spleen CT value ratio in the treatment group were increased more obviously than that in the control group（ 〈0.05）.Conclusion：strengthening spleen and excerting dampness decoction could improve the liver function,Chinese medicine symptom scores and the liver / spleen CT value ratio of NAFLD pateints.