中文摘要：

我国现有癫痫患者约900万,同时还以每年40万的数量递增,是危害我国人口整体素质的重要疾病之一。有20%～30%的癫痫患者对现有的抗癫痫药物治疗不敏感,最终发展成为药物难治性癫痫,其中部分患者经过手术治疗可取得较为满意的疗效,然而,仍有相当数量的患者缺乏手术适应证或术后疗效不佳,因此,不断拓展癫痫的治疗手段,对提高癫痫患者的生存质量具有重要意义。

英文摘要：

The treatment of patients with refractory epilepsy has always been challenging.Despite the availability of multiple antiepileptic drugs,approximately 20%-30% of patients continue to have seizures,and many are not candidates for epilepsy surgery.Currently available treatment options for these unfortunate patients are limited.Brain electric stimulation provides a nondestructive treatment for these patients.Studies of electrical stimulation of the brain in epilepsy treatment begin with the research on cerebellar stimulation.Until now,the potential targets have increased over the years,including cortex,cranial nerve and multiple brain nuclei.With the development of therapeutic brain devices for epilepsy,it is convinced that the brain electric stimulation will become more widely applied in treatment of epilepsy.This overview,combining with literatures and our experiences,briefly summarizes the application of brain electric stimulation in the treatment of epilepsy.