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Use of laser speckle contrast imaging to reveal changes in temperature and blood perfusion in the skin of healthy subjects after administration of heated moxa sticks and Daiwenjiu ointment
  • 分类:S147.2[农业科学—肥料学;农业科学—农业基础科学] TQ424.1[化学工程]
  • 作者机构:[1]Institute of Acupuncture and Moxibustion,China Academy of Chinese Medical Sciences
  • 相关基金:Supported by Study on the Biological Effect and Mechanism of Different Methods Guasha of National Natural Science Foundation(No.81173346); Research of Sensitization and Quantification of Thermo-sensitive Acupoint and its Mechanism from Youth Science Fund Project(No.81102649); External Treatment Of TCM Characteristic Treatment and External Treatment Technology Demonstration Research of the Eleventh Five-Year National Science&Technology Supporting Program(No.2008BAI53B063)
中文摘要:

OBJECTIVE: To investigate the influence of heated moxa sticks( 'moxibustion') and Daiwenjiu ointment(DO) on changes in temperature and blood perfusion volume on the skin of the backs of healthy subjects.METHODS: DO was spread on the left side of the body, and the right side of the body was treated with a heated moxa stick. Images denoting blood perfusion and body temperature were collected 7-8 cm lateral to the spinous process of the sixth thoracic vertebra using laser speckle contrast imaging(LSCI). Data obtained from eight-frame images were analyzed and used to calculate the mean blood perfusion volume. Simultaneously,blood-perfusion images were collected from the body surface and used to compare the change in blood flow on the body surface and the actual position of imaging.RESULTS: After moxibustion, a rapid increase in blood perfusion volume and body temperature was noted in the local skin surface. The maximum blood perfusion volume and body temperature was noted at 20 min(P<0.05). At 80-110 min after the spreading of DO, a gradual increase was noted in blood perfusion volume(P<0.05) and body temperature(P<0.05) compared with the baseline level. The maximum blood perfusion volume was at 110 min.CONCLUSION: Using LSCI, these data revealed a rapid and sharp increase in blood perfusion volume and body temperature after treatment with moxibustion, but the respective changes seen in the DO group were gradual and moderate.

英文摘要:

OBJECTIVE: To investigate the influence of heated moxa sticks( "moxibustion") and Daiwenjiu ointment(DO) on changes in temperature and blood perfusion volume on the skin of the backs of healthy subjects.METHODS: DO was spread on the left side of the body, and the right side of the body was treated with a heated moxa stick. Images denoting blood perfusion and body temperature were collected 7-8 cm lateral to the spinous process of the sixth thoracic vertebra using laser speckle contrast imaging(LSCI). Data obtained from eight-frame images were analyzed and used to calculate the mean blood perfusion volume. Simultaneously,blood-perfusion images were collected from the body surface and used to compare the change in blood flow on the body surface and the actual position of imaging.RESULTS: After moxibustion, a rapid increase in blood perfusion volume and body temperature was noted in the local skin surface. The maximum blood perfusion volume and body temperature was noted at 20 min(P〈0.05). At 80-110 min after the spreading of DO, a gradual increase was noted in blood perfusion volume(P〈0.05) and body temperature(P〈0.05) compared with the baseline level. The maximum blood perfusion volume was at 110 min.CONCLUSION: Using LSCI, these data revealed a rapid and sharp increase in blood perfusion volume and body temperature after treatment with moxibustion, but the respective changes seen in the DO group were gradual and moderate.

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