中文摘要：

瑞香狼毒（Stellera chamaejasme）为瑞香科（Thymelaeaceae）植物,广泛分布于我国西北、华北等地（刘欣等,2004）。据《神农百草经》记载,瑞香狼毒与大戟科（Euphorbiaceae）植物狼毒大戟（Euphorbia fischeriana）、月腺大戟（E.ebracteolata）同作狼毒入药,其性味苦平,全草有毒,有逐水祛痰、破积杀虫之功效（张慧文等,2006）。 瑞香狼毒也是一种极具开发潜力的植物源农药。

英文摘要：

In this work the supercritical fluid extraction with carbon dioxide was applied to extract roots of Stellera chamaejasme.The extracts were evaluated through the antifungal activity against Monilinia fructicola.Furthermore,the active compounds from the extracts were separated by macroporous resin and analyzed using gas chromatography-mass spectrometry（GC-MS）.The results showed that the extracts had strong antifungal activity against M.fructicola with inhibition ratio of 88.71% at 2 000 μg·mL-1,minimum inhibitory concentration（MIC） of 250 μg·mL-1,and minimum fungicidal concentration（MFC） of 2 000 μg·mL-1.After separated with macroporous resin chromatography,fourteen fractions were collected from the extracts.Fraction 4,7,and 12 in a concentration of 2 000 μg·mL-1 presented highly antifungal activity against M.fructicola,with inhibition ratio of 83.97%,80.23%,and 75.69%,respectively.The GC-MS analysis revealed that the main active compounds from fraction 4,7,and 12 included hexanedioic acid;bis（2-ethylhexyl） ester;β-sitosterol;7-methyl-Z-tetradecen-1-ol acetate9;9-hexadecenoic acid,hexadecyl ester,（Z）;1,2-benzenedicarboxylic acid,diisooctyl ester;（3β,24Z）,stigmasta-5,24（28）-dien-3-ol;stigmastan-3,5-diene,and squalene.