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乳腺癌患者预后的相关因素分析
  • ISSN号:1673-6273
  • 期刊名称:《现代生物医学进展》
  • 分类:R737.9[医药卫生—肿瘤;医药卫生—临床医学]
  • 作者机构:[1]第四军医大学附属唐都医院普外科,陕西西安710032, [2]解放军第十医院,甘肃武威733000
  • 相关基金:国家自然科学青年基金项目(81001181)
中文摘要:

目的:探讨影响乳腺癌患者预后的相关因素。方法:回顾性分析2008年1月~2009年2月我院收治的81例乳腺癌患者的临床、病理及随访资料。结果:所有患者均手术治疗并经病理证实,年龄45岁以上的乳腺癌患者的五年生存率为82.6%,显著高于45岁及其以下者(45.7%,P〈0.05);肿瘤直径为3 cm及其以下的乳腺癌患者的五年生存率为81.5%,显著高于肿瘤直径为3 cm以上者(40.7%,P〈0.05);无淋巴结转移的乳腺癌患者五年生存率明显高于有淋巴结转移的乳腺癌患者(P〈0.05);I期、II期、Ⅲ期、Ⅳ期的乳腺癌患者五年生存率分别为93.8%、73.0%、52.9%、0%,不同临床分期的乳腺癌患者的五年生存率比较差异均有统计学意义(P〈0.05)。结论:乳腺癌的治疗以手术为主,年龄、肿瘤大小、淋巴结转移、临床分期与患者的预后密切相关。

英文摘要:

Objective: To investigate the related factors affecting the prognosis of patients with breast cancer. Methods: A retrospective analysis was made on the clinical and pathological and follow-up data of 81 cases of breast cancer from Jan.2008 to Feb.2009 in our hospital. Results: All the cases received surgical treatment and were pathologicallly confirmed, the 5-year survival rate of breast cancer patients over 45 years old was 82.6%, which was significantly higher than those patients aged 45 years old and below (45.7%, P〈0. 05). The 5-years survival rate of breast cancer patients whose tumor diameter were less than or equal to 3 cm was 81.5%, it was significantly higher than those whose tumor diameter were greater than 3cm (40.7%, P〈0.05). The 5-year survival rate of breast cancer patients without lymph node metastases was significantly higher than those breast cancer patients with lymph node metastases in (P〈0.05). The 5-year survival rates of breast cancer patients at stage I, stage II, stage III, stage IV were 93.8%, 73%, 52.9%, 0%, significant differences were found in the 5-year survival rates between breast cancer patients at different clinical stages (P〈0.05). Conclusion: Breast cancer was mainly treated by surgery, age, tumor size, lymph node metastasis, clinical stage were closely correlated with its prognosis.

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期刊信息
  • 《现代生物医学进展》
  • 中国科技核心期刊
  • 主管单位:黑龙江省卫生厅
  • 主办单位:黑龙江省红十字医院 黑黑龙江省红十字医院 黑龙江省森林工总医院
  • 主编:申宝忠
  • 地址:哈尔滨市南岗区花园街184号403
  • 邮编:150001
  • 邮箱:biomed_54@126.com
  • 电话:0451-82583800 53658268
  • 国际标准刊号:ISSN:1673-6273
  • 国内统一刊号:ISSN:23-1544/R
  • 邮发代号:14-12
  • 获奖情况:
  • 国内外数据库收录:
  • 被引量:33230