蛋白质是生命的物质基础,对蛋白质中所含基团间相互作用的研究十分重要.有机溶剂对蛋白质的溶解度、变性行为和解缔等都有很大影响.酰胺是肽的基本结构单元,而且在蛋白质的二级结构中与酰胺联系的氢键对蛋白质的稳定起着十分重要的作用.作为蛋白质模型化合物热力学性质研究的一部分,本文报道了甲酰胺在乙二醇水溶液中的稀释焓.
The dilution enthalpies of formamide in a CSC-4400 isothermal calorimeter at 298. 15 K. range of ethylene glycol mass fraction(0%-40% ) aqueous ethylene glycol solutions were determined by using The homogeneous enthalpic interaction coefficients in the were calculated according to the excess enthalpy concept. The results show that enthalpic pair interaction coefficients h2 of formamide are negative in aqueous ethylene glycol solutions and pass through a minimum at w ≈0. 20 of ethylene glycol in mixed solvents.