中文摘要：

目的利用频域光学相干断层扫描（SD-OCT）对青光眼患者盘周视网膜神经纤维层（RNFL）厚度进行观察测量,比较非Follow-up模式和Follow-up模式测量结果的可重复性。方法连续收集就诊于中国医科大学附属第一医院的青光眼患者38例,随机选择患者一侧眼进行测量。利用SD-OCT分别采用非Follow-up模式和Follow-up模式对盘周RNFL厚度进行测量,比较2种检查模式的组内标准差（Sw）、变异系数（CV）和组内相关系数（ICC）。结果非Follow-up模式测量RNFL厚度,Sw为3.67μm（视盘全周）-10.58μm（鼻侧象限）,CV为2.60%（视盘全周）-10.09%（鼻侧象限）,ICC为0.768（鼻侧象限）-0.974（视盘全周）。Follow-up模式测量RNFL厚度,Sw为1.42μm（视盘全周）-3.31μm（鼻上扇区）,CV为1.27%（视盘全周）-3.00%（鼻侧象限）,ICC为0.982（鼻侧象限）-0.996（视盘全周）。Follow-up模式测量的重复性优于非Follow-up模式。结论利用SD-OCT测量盘周RNFL厚度,Follow-up模式的可重复性优于非Follow-up模式,达到了临床应用标准,可用于临床青光眼的检查和长期随访。

英文摘要：

Objective To compare the reproducibility of retinal nerve fiber layer （RNFL） thickness measured by No Follow-up and Follow-up patterns of high-resolution spectral domain-optical coherence tomography （SD-OCT） in glaucoma. Methods A total of 38 eyes from 38 patients with glaucoma who admitted to the First Hospital, China Medical University were sequentially included. RNFL thickness was measured by No Follow-up or Follow-up patterns of SD- OCT. Within-subject standard deviation （Sw）, coefficient of variation （CV）, and intraclass correlation coefficient （ICC） using the two measuring patterns were assessed. Results For RNFL thickness measured by No Follow-up pattern, Sw was 3.67 μm （ global average, G） to 10.58 μm （nasal, N）, CV was 2.60% （G） to 10.09% （N）, and ICC was 0.768 （N） to 0.974 （G）. For RNFL thickness measured by Follow-up pattern, Sw was 1.42 μm （G） to 3.31 μm （superior-nasal, NS）, CV was 1.27% （G） to 3.00% （N）, and ICC was 0.982 （N） to 0.996 （G）, respectively. Follow-up pattern had higher reproducibility for the measurements of RNFL thickness than No Follow-up pattern. Conclusion For the measurements of RNFL thickness, Follow-up pattern has higher reproducibility than No Follow-up pattern, indicating that RNFL thickness measured by Follow-up pattern of SD-OCT is a reliable tool for assessing longitudinal change and follow-up in glaucoma.