目的探讨不同时间远红外线照射对维持性血透患者自体动静脉内瘘的临床疗效。方法选取使用自体动静脉内瘘的维持性血透1年以上的患者80例,分为20 min组、40 min组、60 min组和对照组各20例,前3组每次透析时分别予以远红外线照射20、40和60 min,每周3次,治疗6个月。对照组仅予规律透析治疗。比较4组的血流量变化及内瘘功能障碍发生率,并检测单次透析前后4组患者血高敏C反应蛋白(hs CRP)和白细胞介素-8(IL-8)浓度。结果与对照组相比,经过半年每周3次远红外线照射治疗后,20 min、30 min、40 min组血流量增值均明显高于对照组(P〈0.05);40 min及60 min组血流量增值与20 min组相比明显增加(P〈0.05);40 min组与60 min组间血流量增值差异无统计学意义(P〉0.05)。20 min、30 min、40 min组经半年远红外照射治疗后,血hs CRP及IL-8差值与对照组相比有下降趋势,但差异无统计学意义(P〉0.05);40 min及60 min组较20 min组下降明显,差异无统计学意义(P〉0.05);40 min组与60 min组间差异无统计学意义(P〉0.05)。结论选择每周3次,每次40 min的远红外照射的治疗方式对维持性透析患者自体动静脉内瘘可以达到最佳效果,值得临床推广使用。
Objective To investigate the treatment effect of far infrared radiation on autogenous arteriovenous fistula in patients on maintenance hemodialysis. Methods Patients on autogenous arteriovenous fistula for more than one year were divided into the 20 min group, 40 rain group, 60 min group and the control group. Each group had 20 patients. The first 3 groups received far - infrared radiation for 20, 40 and 60 rain at each time of dialysis, respectively, 3 times a week, for 6 months. The control group only received regular dialysis treatment. Blood flow changes and the incidence of fistula dysfunction were recorded. Levels of high - sensitivity C - reactive protein (hsCRP) and interleukin - 8 ( IL - 8 ) were detected by ELISA. Results Compared with the control group, after far - infrared radiation therapy for six months, increases of blood flow in 20 rain, 30 rain, 40 min groups were significantly higher ( P 〈 0. 05 ). Blood flow increase in the 40 min and 60 rain groups were higher than 20 min group ( P 〈 0. 05 ). There was no statistically significant difference in blood flow increase between the 60 min and 40 min group. After six months of far - infrared radiation therapy, serum hsCRP and IL - 8 decreased compared with the control group, but the differences among 20 min, 30 min, 40 min groups were not statistically significant (P 〉 0. 05 ). Levels of serum hsCRP and IL - 8 were lower in the 40 min group and 60 min group than the 20 min group, but similar between the 40 rain group and the 60 min group. Conclusion Far - infrared radiation session of 40 min, three times a week delivers the best treatment effects and worthy of clinical application on autogenous arteriovenous fistula in maintenance hemodialysis patients.