中文摘要：

结合Friston的BOLD动力学模型与Agnes Aubert建立的脑电生理和代谢藕合模型，提出了一种扩展的BOLD动力学模型．对改进的模型讨论了血液动力学模型血流的非线性特性，把脑的新陈代谢与血动力学模型的血流、血体积关联起来，并对BOLD模型中的输入信号进行研究．得到了能更好地模拟实际生理过程的仿真结果．

英文摘要：

Based on Friston＇s Blood Oxygenation Level Dependent （BOLD） dynamic model, an extended BOLD dynamic model is proposed in combination with Agnes Aubert＇s coupling model of brain electrical activity and metabolism. In this model, the cerebral metabolism is connected with blood flow or blood volume of the hemo-dynamic model after discussion of nonlinear character of the blood flow in hemo-dynamic model. The better simulation effect of physiological process is achieved with the restructured input signal of the BOLD model.