中文摘要：

应用AmpFLSTR Y-filer PCR Amplification Kit荧光标记复合扩增试剂盒（ABI公司）,对曲阜地区11 18名孔姓男性个体血样DNA进行PCR,扩增,统计分析17个Y-STR基因座的遗传学参数。实验结果显示,17个基因座除DYS385a/b基因座检出51个单倍型外,其余基因座上分别检出4-11种等位基因,等位基因频率分布在0.0009-0.8265之间。由17个基因座组成的YH单倍型系统共检出206种单倍型。根据Y-STR单倍型推断了Y-SNP单倍群,发现曲阜孔姓有3种高频单倍群：C3、Q1a1和O3,前两者有着明显的单祖先扩散结构,最可能是孔子类型。本实验通过对曲阜地区孔姓人群群体17个Y染色体短串联重复序列基因座遗传多态性的调查,记录、保存孔姓人群遗传学数据。

英文摘要：

Blood samples were collected from 1118 male individuals of Kong clans in the Qufu Prefecture of Shandong Province. Seventeen Y- chromosomal short tandem repeats （STR） loci were amplified in one tube by using the AmpFLSTR Y-filerTM PCR Amplification Kit for each person, and then the frequency of alleles and genotypes of group was obtained. The results show that, except DYS385a/b locus was detected 51 haplotypes, the rest loci were detected from 4 to 11 alleles, the allele frequency distribute from 0.0009 to 0.8265. Totally, 206 haplotypes were detected in the YH haplotype system consisting of 17 loci. According to the Y-STR haplotypes, we inferred the Y-SNP haplogroups. We found three high frequency haplogroups among the Kong clans, i.e., C3, Qlal, and 03. Both C3 and Qlal exhibited a mono-ancestor diffusion structure, indicating that either of them may be the haplogroup of Confucius. By investigating the 17 Y- STR loci among the Kong clans from Qufu Prefecture, we recorded the basic date of Kongpopulation.