中文摘要：

目的研究海洋真菌Y26-02发酵液的乙酸乙酯萃取部分,对其中的化学成分进行分离鉴定。方法采用硅胶、Sephadex LH-20柱色谱以及制备型高效液相色谱等手段进行分离纯化,通过理化性质和各种波谱数据对这些化合物进行结构鉴定。结果从海洋真菌Y26-02菌液的乙酸乙酯萃取部分分离得到7个化合物,分别鉴定为灰黄霉素（griseofulvin,1）、表灰黄霉素（epigriseofulvin,2）、异灰黄霉素（isogriseofulvin,3）、脱氯表灰黄霉素（dechloroepigriseofulvin,4）、脱氢灰黄霉素（de-hydrogriseofulvin,5）、4′-丁氧基异灰黄霉素（4′-butoxyisogriseofulvin,6）、2′-丁氧基表灰黄霉素（2′-butoxyepigriseofulvin,7）。结论这7个化合物均为首次从该真菌的代谢产物中分离得到,其中化合物6、7是新天然产物。

英文摘要：

Objective To isolate and identify the chemical constituents of the ethyl acetate extract part of the marine fungus Y26-02 fermentation broth.Methods The compounds were isolated by silica gel column,Sephadex LH-20 column chromatography and HPLC techniques.And these compounds were identified by the physico-chemical properties and spectral analysis.Results Seven compounds were obtained and identified as griseofulvin（1）,epigriseofulvin（2）,isogriseofulvin（3）,dechloroepigriseofulvin（4）,dehydrogriseofulvin（5）,4′-butoxyisogriseofulvin（6）and 2′-butoxyepigriseofulvin（7）.Conclusions All mentioned compounds are firstly isolated from the fungus Y26-02.Compounds 6,7 are isolated from natural products for the first time.