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慢性鼻窦炎鼻分泌物中嗜酸粒细胞阳离子蛋白的表达及临床意义
  • ISSN号:1000-9965
  • 期刊名称:《暨南大学学报:自然科学与医学版》
  • 时间:0
  • 分类:R765[医药卫生—耳鼻咽喉科;医药卫生—临床医学]
  • 作者机构:[1]中国医科大学北京顺义医院耳鼻喉科,北京101300, [2]首都医科大学附属朝阳医院耳鼻喉科,北京100005
  • 相关基金:国家自然科学基金项目(81070772)
中文摘要:

目的:探讨鼻内镜下动力切削系统治疗对鼻前庭囊肿患者CRP、TNF-α、IL-6和IL-8的影响。方法:选取2012年6月至2013年1月我院收治的鼻前庭囊肿患者163例,随机分为两组。实验组(80例)行鼻内镜下动力切削系统行囊肿切除术,对照组(83例)给予微波治疗。观察并比较两组患者手术前后血清CRP、TNF-α、IL-6和IL-8水平的变化情况,并比较两组患者手术情况、术后并发症及远期疗效。结果:与对照组比较,实验组手术时间较长,术中出血量较多,差异具有统计学意义(P〈0.05),实验组术后感染率较低,术后复发率较低;术后CRP、TNF-α、IL-6和IL-8水平升高,与对照组相比,实验组各项指标较高(P〈0.05)。结论:鼻内镜下动力切削系统治疗鼻前庭囊肿具有较好的临床治疗效果,且复发率低,值得临床推广。

英文摘要:

Objective: To investigate the clinical efficacy of endoscopic dynamic cutting system for nasal vestibular cyst and its effect on the level of CRP, TNF- α, IL-6 and IL-8. Methods: 163 cases with nasal vestibular cyst that were treated in our hospital from June 2012 to January 2013 were selected and randomly divided into two groups. 80 patients in the experimental group were given the endoscopic dynamic cutting surgery for cyst resection, while another 83 patients in the control group were treated with microwave therapy. Then the level of CRP, TNF- α, IL-6 and IL-8 of patients in the two groups were observed and compared before and after the treatment, and the operative situations, the incidence of postoperative complications and the long-term effects of two groups were compared. Results: The operation time and intraoperative bleeding of experiment group were more than the control group(P〈0.05),however, the postoperative infection rate and recurrence rate of experiment group was lower(P〈0.05) compared with the control group.The level of CRP, TNF-α, IL-6 and IL-8 was higher than before operation, and compared with the control group, the indexes in the experimental group were higher(P〈0.05). Conclusions: Endoscopic treatment of nasal vestibular cyst dynamic cutting system has a better clinical therapeutic effect, worthy of clinical application.

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期刊信息
  • 《暨南大学学报:自然科学与医学版》
  • 中国科技核心期刊
  • 主管单位:广东省教育厅
  • 主办单位:暨南大学
  • 主编:刘颖
  • 地址:广州市黄埔大道西601号
  • 邮编:510632
  • 邮箱:jdxblk@sina.com
  • 电话:020-85224092
  • 国际标准刊号:ISSN:1000-9965
  • 国内统一刊号:ISSN:44-1282/N
  • 邮发代号:46-257
  • 获奖情况:
  • 2009年全国高校科技期刊优秀编辑质量奖,2010年获教育部科技司颁发“第三届中国高校优秀期...,2011年获广东省科学技术厅“第四届广东省优秀科技...
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  • 美国化学文摘(网络版),美国数学评论(网络版),德国数学文摘,美国剑桥科学文摘,英国动物学记录,中国中国科技核心期刊,中国北大核心期刊(2004版),中国北大核心期刊(2008版),中国北大核心期刊(2011版),中国北大核心期刊(2014版)
  • 被引量:9165