中文摘要：

目的探讨序贯器官衰竭估计（SOFA）评分对急诊严重感染性患者预后进行预测的关系。方法选取2013年5月-2014年5月92例急诊严重感染性患者为研究对象,按患者结局将其分为生存组71例和死亡组21例,计算T0SOFA和T48SOFA,得出SOFA,分别观察入院T0SOFA评分、T48h的△SOFA评分与患者病死率的关系,分析SOFA评分在预测急诊严重性感染性患者预后中的作用。结果两组患者入住急诊当日对T0SOFA评分进行比较,死亡组评分（11.9±3.5）分,高于生存组（7.6±2.3）分,治疗48h后的T48SOFA及SOFA分别进行比较,死亡组评分仍然高于生存组,差异均有统计学意义（P〈0.05）;随着SOFA评分分值的增高,病死率呈上升趋势,且在SOFA评分为0-3分时病死率为0,在〉15分时病死率为100.0%,差异有统计学意义（P〈0.05）;两组患者平均器官损伤数比较,生存组为（3.1±1.3）个、死亡组为（4.5±1.7）个,死亡组多于生存组,差异有统计学意义（P〈0.05）,两组在心血管循环系统、呼吸系统及肾脏系统器官中最大SOFA评分比较,死亡组评分得分高于对照组,差异均有统计学意义（P〈0.05）,在其他系统评分中比较,差异无统计学意义。结论 SOFA评分能较好的预测急诊严重感染性患者预后,可在临床推广应用。

英文摘要：

OBJECTIVE To investigate the sequential organ failure assessment（SOFA）score in prediction of prognosis of patients with emergency severe infections.METHODS A total of 92 patients with emergency severe infections who were treated from May 2013 to May 2014 were recruited as the study objects and divided into the survival group with 71 cases and the death group with 21 cases according to the outcomes.The T0 SOFA and T48 SOFA were calculated to determine SOFA;the relationship between the T0 SOFA score at admission,△SOFA score at T48 and the mortality rate was observed;the value of the SOFA score in the prediction of prognosis of the patients with emergency severe infections was evaluated.RESULTS The T0 SOFA score of the death group was（11.9±3.5）points on the day of enrollment to emergency department,higher than（7.6±2.3）points of the survival group.The T48 SOFA score and SOFA score of the death group remained higher than those of the survival group after the treatment for 48 hours,with significant difference（P〈0.05）.The mortality rate was increased with the elevation of the SOFA score,it was 0when the SOFA score varied from 0to 3points and was 100.0% when the SOFA score was more than 15 points,with significant difference（P〈0.05）.The average number of damaged organs of the death group was（4.5±1.7）,more than（3.1±1.3）of the survival group,with significant difference（P〈0.05）.The highest SOFA score of the cardiovascular circulatory system,respiratory system,and renal system organs of the death group was higher than that of the control group,with significant difference（P〈0.05）;there was no significant difference in the score of other systems.CONCLUSION The SOFA score can effectively predict the prognosis of the patients with acute severe infections,and it is worthy to be promoted in the hospital.