中文摘要：

目的研究地方性砷中毒（地砷病）病区改良饮用水前后病妇头发中砷及其他微量元素含量的变化，确定改水对病妇体内砷及其他微量元素的影响。方法用扫描质子微探针测定病妇单根头发中砷及其他10种微量元素的含量分布。结果发现As、Fe、Cu、Ni、Mn、Ti、Sr、K在地砷病重病人头发中平均含量最高，轻病人次之，正常人最低；而Ca和Zn在健康人头发中浓度最高。重病人、轻病人发根与发梢上述7种元素含量差异显著（P〈0．05或P〈0．001）。结论地砷病区对改水减砷工程大大降低了病人体内的砷含量，促进了微量元素的代谢平衡。

英文摘要：

Objective In order to know the effects of improving water in endemic arsenism area on concentrations of As and other trace elements in human body, distributions of arsenic and other trace elements in single hair of female patients who have been drinking improved water for one year were studied. Methods The concentrations of 11 elements in single hair of serious and minor endemic arsenism female patients were determined by scanning proton microprobe （ SPM ）. Results The highest concentrations of As, Fe, Cu, K, Mn, Ni, St, and Ti were found in serious endemic arsenism group, while the lowest contents of these elements were found in normal control group. The concen tration of Ca and Zn were highest in healthy people hair. There were extremely significant differences in contents of he above mentioned elements （ P 〈 0. 05 or P 〈 0. 001）. Conclusions Improving drinking water is an effective way for reducing As in patient bodies. Meanwhile, homeostasis of other trace elements were maintained.