目的:研究白芥子不同配比穴位贴敷防治支气管哮喘所出现的皮肤反应与疗效之间关系。方法:将所纳入的90例支气管哮喘患者随机分为A、B、C3组,每组30例。贴敷药物中除白芥子外,余药相同。A组全部为生白芥子,B组生白芥子、炒白芥子各半,C组全部为炒白芥子。三伏天穴位贴敷,每伏贴敷一次,共3次。观察由不同配比白芥子而引起的皮肤反应以及各组疗效。结果:穴位贴敷后A、B、C3组皮肤反应积分依次降低,3组皮肤反应差异有统计学意义(P〈0.05),A、B、C3组临床总有效率分别为93.33%、90.00%、73.33%,3组疗效组间比较无显著差异(p〉0.05)。结论:穴位贴敷防治支气管哮喘是一种行之有效的方法,随生白芥子比例增加3组患者皮肤反应逐渐加重,但并非皮肤反应越强疗效越显著,适度的皮肤反应即可达到良好的疗效。
Objective:To study the relationship between the skin reactions and efficacy of preventing and treating bronchial asthma by acupoint application with different dose ratios of semen sinapis. Methods : 90 cases of bronchial asthma were randomly divided into group A, B and C,30 cases in each. In addition to semen sinapis different doses, other sticking drugs were the same in each group. In group A semen sinapis were all raw and in group B half semen sinapis were raw and the other half were roasted. In group C semen sinapis were all roasted. All of the patients were treated by acapoint sticking therapy once every ten days in the dog - days, a total of three times. The skin reactions and efficacy of each group caused by different dose ratios of semen sinapis were observed. Results : The skin reaction integral of group A, B and C reduced in turn and the difference was significant in statistics ( P 〈 0.05 ). The total effective rate of group A, B and C were 93.33 % ,90.00% and 73.33 %, respectively. There was no significant difference among group A, B and C ( P 〉 0.05 ). Conclusion : Preventing and treating bronchial asthma with acupoint application was effective. With the increase in the proportion of raw semen sinapis, the skin reactions gradually worsened, but not stronger skin reactions more significant effect. Moderate skin reactions could receive good efficacy.