中文摘要：

首次合成出水溶性两亲性含胆固醇基的羧甲基纤维素钠衍生物（CCSD）。羧甲基纤维素钠（CMCNa）先被质子化成羧甲基纤维素（CMC），然后在偶联剂和催化剂的作用下CMC与胆固醇于室温进行反应，产物纯化后用碳酸钠中和至pH=7。用红外光谱法对CCSD产物进行了结构分析，1733cm^-1的伸缩振动峰证实CMC中的羧酸与胆固醇的羟基发生了酯化反应。荧光光谱法研究了所合成的CCSD在0．15mol/L氯化钠水溶液中的胶束化行为，其临界聚集浓度为O．62g／L。CCSD在亚浓溶液中呈现非牛顿流体中剪切稀化的特性，CCSD分子间存在疏水性胆固醇基之间的非极性-非极性相互作用力。

英文摘要：

The water soluble amphiphilic cholesteryl-bearing carboxymethylcellulose sodium derivative（CCSD） was first synthesized with the help of coupling agent and catalyst at room temperature. The esterification between carboxymethylcellulose and cholesterol was characterized by FTIR spectroscopy. The micelle behavior of CCSD was studied by fluorescence spectroscopy, indicating that CCSD can form micelle in 0.15 mol/L NaCl solution and its critical aggregation concentration（CAC） is 0.62 g/L. CCSD solution exhibits a pseudoplastic fluid behavior, and the intermolecular non-polar/non-polar interactions between cholesteryl groups exists in its semidilute regime.