目的研究分析无抽搐电休克(MECT)对精神分裂症患者症状和执行功能的影响。方法选取我院2010年12月~2011年12月72例精神分裂症患者,随机分为观察组和对照组各36例,观察组采取MECT联合抗精神病药物治疗,对照组单纯采取抗精神病药物治疗,治疗前后皆采取阳性与阴性症状量表(PANSS)与威斯康星卡片分类任务(WCST)对患者的临床症状及执行功能进行评价。结果两组在治疗后的第3、6周末PANSS的阳性与阴性症状评分与治疗前比较均明显下降(P〈0.05),观察组下降程度更为显著(P〈0.05)。结论MECT联合药物治疗精神分裂症的效果明显.能够显著改善精神病症状和执行能力。
Objective To study the effect of modified electroconvulsive therapy (MECT) on schizophrenia patients" symptoms and executive function effect. Methods From Dec 2010 to Dec 2011 in our hospital 72 cases of schizophrenia patients, were randomly divided into the observation group and control group, each 36 cases, observation group to take MECT combined with antipsychotic drug treatment, the control group only taking antipsychotic medication, before and after treatment are to take positive and negative symptom scale (PANSS) and the Wisconsin Card Sorting Task (WCST) on the patients" clinical symptoms and executive function evaluation. Results The two groups after treatment in third,6 weekend PANSS positive and negative symptom score compared with before treatment were significantly decreased (P 〈 0.05),the observation group decreased more significantly (P 〈 0.05). Conclusion MECT combined with drugs in the treatment of schizophrenia effect obviously, can significantly improve psychiatric symptoms and exec- utive ability.