中文摘要：

研究双亚砜膦配体（BiSO-P）亚砜基团的Bronsted碱性在协同催化反应中的作用. 1H NMR研究表明双亚砜膦与醇和胺等质子试剂形成氢键; 并将此类配体应用于钯催化的不对称醚化和胺化反应, 最高获得99% ee. 研究发现氢键的存在能有效提高反应的ee值, 配体亚砜基团在反应过程中同时起着Lewis和Bronsted碱的作用.

英文摘要：

A serious of bissulfoxide-phosphine ligands are examined on the Bronsted basicity of sulfinyl moiety. The effect of secondary binding property of the ligand is demostrated in Pd-catalyzed asymmetric allylic etherification and amination （up to 99% ee）. And the application scope of this methodology to hydrogen-donor nucleophiles is investigated.