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十全大补汤联合肠内营养支持在肺癌手术患者中的应用效果
  • ISSN号:1672-0482
  • 期刊名称:《南京中医药大学学报》
  • 时间:0
  • 分类:R273[医药卫生—中医肿瘤科;医药卫生—中西医结合;医药卫生—中医学]
  • 作者机构:[1]河南省南阳市中心医院胸外科,河南南阳473000
  • 相关基金:国家自然科学基金(81172240)
中文摘要:

目的探讨十全大补汤联合肠内营养支持对肺癌手术患者免疫功能及临床疗效的影响。方法选取2011年3月-2013年5月于我院行肺癌手术的72例肺癌患者作为研究对象,随机分为对照组和观察组,每组各36例,术后2组患者均给予常规早期肠内营养,观察组患者在此基础上给予口服十全大补汤。治疗后对2组患者手术前后血液免疫指标水平变化、治疗后中医证候评分及免疫功能评价结果进行比较分析。结果 12组患者术后第1天血液免疫各项指标水平均较术前明显降低,而在术后第8天升高且明显高于术前水平(P〈0.05);2组间比较显示,观察组患者术后第8天的IgM、CD3+、CD4+及CD4+/CD8+水平均较对照组患者明显升高(P〈0.05);2观察组患者术后第4天和术后第8天的中医证候积分均较对照组患者明显降低(P〈0.05);3与对照组相比,术后观察组免疫功能提高患者明显增加,而免疫功能下降患者明显减少,差异均具有统计学意义(P〈0.05)。结论十全大补汤联合肠内营养支持可有效提高患者免疫功能并改善其临床症状,相比常规肠内营养支持更加有利于患者术后恢复。

英文摘要:

OBJECTIVE To discuss the influence of Shiquandabu Decoction together with enteral nutrition for the immune function and clinical curative effect of lung cancer patients after surgery. METHODS 72 patients with lung cancer after surgery from March 2011 to May 2013 in our hospital were chosen as the research objects and were randomly divided into the control group(36 cases) and observation group(36 cases). The patients of two groups were given conventional early postoperative en- teral nutrition and then the patients of observation group were given Shiquandabu Decoction and comparative study was made a- mong the level change of blood immune indexes before and after operation, TCM symptom score after treatment and immune function evaluation of two groups. RESULTS ① the indexes of the blood and immune of patients in both groups were signifi- cantly lower on the first day after the surgery, but on the eighth day, the indexes were significantly higher than those before the surgery(P〈0.05). The comparison between the two groups showed that the scores of IgM, CD3+,CD4+ and CD4+/ CD8+ of the observation group significantly increased than those of the control group(P〈0.05). ②The TCM syndrome score of patients in the observation group in the fourth and eighth day were significantly decreased than those of patients in the con- trol group (P〈0.05). ③ Compared with the control group, the number of the patients who had major immune function im- provement after the surgery increased significantly in the observation group and the number of patients who had the decreasing of immune function decreased and the differences were of statistical importance(P〈0.05). CONCLUSION Shiquandabu De- coction together with enteral nutrition can effectively improve the immune function and clinical symptoms. Compared with con- ventional enteral nutrition, the combination is more beneficial to the postoperative recovery of patients.

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期刊信息
  • 《南京中医药大学学报》
  • 北大核心期刊(2011版)
  • 主管单位:江苏省教育厅
  • 主办单位:南京中医药大学
  • 主编:范欣生
  • 地址:南京市仙林大学城仙林大道138号
  • 邮编:210023
  • 邮箱:
  • 电话:025-85711934 85811935
  • 国际标准刊号:ISSN:1672-0482
  • 国内统一刊号:ISSN:32-1247/R
  • 邮发代号:28-232
  • 获奖情况:
  • 国内外数据库收录:
  • 美国化学文摘(网络版),英国农业与生物科学研究中心文摘,波兰哥白尼索引,中国中国科技核心期刊,中国北大核心期刊(2008版),中国北大核心期刊(2011版),中国北大核心期刊(2014版)
  • 被引量:18464