研究了抗癌药物冬凌草甲素在悬汞电极上的电化学行为。在NaAc-NaOH(pH7.8)的缓冲溶液中,冬凌苹甲素有一受吸附控制的还原峰,峰电位为-1.150V,峰电流与冬凌草甲素浓度在7.25×10^-7~1.01×10^-6mol/L范围内有良好的线性关系,检出限为1.45×10^-7mol/L(S/N=3)。对冬凌草片剂实际样品中冬凌草甲素含量测定,结果满意。
The electrochemical behavior of idinonine (IDN) at the hanging mercury electrode has been investigated. In the acetic acid buffer solution (pH 7.8), a adsorptlon-drlven reduce peak of idinonine is obtained with the peak potentials of -1. 150 V(vs. SCE). The peak currents have a linear relationship with IDN concentrations in the range of 7.25 ×10^-7-1. 01×10^-6mol/L with the detection limit of 1.45 ×10^-7 mol/L. Based on this method, the idinonine content in rabdosia rubescens tablet was determined with satisfactory. Furthermore, the electrode process is also discussed simply.