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中文摘要：
采用MgO、KH2PO4、β-TCP、葡萄糖作为骨水泥的固相,磷酸溶液作为液相,制备可注射镁基磷酸钙骨水泥（IMPC）。考察液固比（LPR）、MgO含量、葡萄糖含量变化对IMPC胶凝性能和力学性能的影响。实验结果显示：液固比和缓凝剂葡萄糖含量增大均会导致凝结时间变长和抗压强度下降,但有益于可注射性;随MgO含量增大,凝结时间缩短,可注射率降低,但抗压强度提高。采用正交实验法确定MgO含量26wt%,液固比0.30 mL/g,葡萄糖含量6wt%时得到的IMPC综合性能良好,水化过程缓和,放热量低。该IMPC有望成为一种新型骨粘结材料。
英文摘要：
Injectable magnesium-calcium phosphate cements （IMPC） was prepared using magnesium oxide （MgO）, monopotassium phosphate （KH2PO4）, β-tricalcium phosphate （β-TCP）, glucose and phosphoric acid solution. The effects of liquid to powder ratio（LPR）, contents of MgO and glucose on IMPC＇s gelling and mechanical properties were investigated. The results showed that increase of LPR and glucose content resulted in increased IMPC setting time and injectability, and decreased compressive strength. With the MgO content decreasing, the setting time and the in- jectability were decreased, whereas the compressive strength was increased. To obtain optimal formula for the new IMPC, the MgO and glucose contents and LPR were selected based on orthogonal experiments, and the result was 26wt% MgO, 6wt% glucose and 0.30 mL/g LPR. The new IMPC has moderate hydration with low exothermic reaction and ideal hardening performance, indicating that it may be used as a novel bone adhesive material.
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