中文摘要：

目的：探讨单纯T波倒置且室壁厚度未达心尖肥厚型心肌病标准患者的心脏MRI特征。方法回顾性搜集2012年6月至2014年6月31例单纯T波倒置但室壁厚度未达心尖肥厚型心肌病标准的患者（患者组）和32名正常志愿者（对照组），按美国心脏学会17节段法测量左心室各节段厚度及心尖角。描述两组受试者左心室壁自基底部至心尖部厚度的变化规律，以及室间隔与游离壁厚度的差别，测量心尖部最大厚度与第4段的比值。心尖部与左心室中部、基底部厚度的差别采用单因素方差分析，两组受试者室壁厚度、心尖角及射血分数等心脏MRI功能参数的比较采用成组t检验。结果对照组左心室壁厚度自基底部至心尖部呈现逐渐变薄的趋势，基底部、中部、心尖部心肌厚度分别为（7.51±0.87）、（6.27±1.11）、（3.57±0.52）mm，差异具有统计学意义（F=171.78，P〈0.01）；心尖部最厚节段与第4段的比值为0.63±0.20。单纯T波倒置患者组失去左心室壁自基底部至心尖部逐渐变薄的趋势，基底部、中部、心尖部心肌厚度分别为（7.70±0.92）、（6.55±0.94）、（7.35±1.14）mm，差异具有统计学意义（F=6.81，P〈0.01）；最厚心尖段与第4段的比值为1.14±0.24。患者组心尖部心肌厚度大于对照组，差异具有统计学意义（t=－11.81，P〈0.01）。患者组心尖角（85.21°±12.09°）较对照组（114.99°±10.88°）明显变小，差异具有统计学意义（t=－10.27，P〈0.01）。结论单纯T波倒置患者左心室壁厚度虽未达肥厚型心肌病诊断标准，但左心室形态较正常人已发生明显改变，应该考虑早期或隐匿期心尖肥厚型心肌病的可能。

英文摘要：

Objective To investigate the cardiac MRI characteristics of patients with pure T-wave inversion and wall thickness less than apical hypertrophic cardiomyopathy diagnostic criteria. Methods Thirty-one patients from June 2012 to June 2014 with pure T-wave inversion and 32 healthy controls were retrospectively enrolled into this study. The left ventricular （LV） wall thickness was measured based on an AHA 17-segment model, as well as the apical angles （apA）. The variations of LV thickness from base to apex, from the septum to free wall, and the ratio of maximal apical thickness to segment 4 were calculated and analysed. One-way ANOVA was used to analysis the thickness differences among the basal, middle and apical walls of left ventricular. In addition, student t test was also used to compare the differences of apical thickness, apA, LV ejective fraction and other cardiac function parameters of MRI between the two groups.＆amp;nbsp;In control groups the LV wall showed a trend of gradual thinning from base to apex. The thicknesses of basal, middle and apical were （7.51 ± 0.87）, （6.27 ± 1.11）, （3.57 ± 0.52） mm, a statistically significant difference （F=171.78, P〈0.01）. The ratio of maximal apical segment to segment 4 was 0.63±0.20. The LV wall of patients with pure T-wave inversion lost the trend of gradual thinning from base to apex. The thicknesses of basal, middle and apical also showed statistically significant difference （F=6.81, P〈0.01） , which were （7.70 ± 0.92）, （6.55 ± 0.94）, （7.35 ± 1.14） mm, respectively. The ratio of the maximal apical thickness to segment 4 was 1.14 ± 0.24 in patients. The apical thickness of patients was significantly greater than that of control＇s （t=-11.81, P〈0.01）. The apA of patients were significantly decreased as controls （85.21° ± 12.09° and114.99° ± 10.88° , t=-10.27, P〈 0.05）. Conclusions Although in patients with pure T-wave inversion, even if the wall thickness of LV less than the apical hypertrophic cardi