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胃肠舒片治疗骨科术后便秘的临床研究
  • ISSN号:1673-6273
  • 期刊名称:《现代生物医学进展》
  • 分类:R687[医药卫生—骨科学;医药卫生—临床医学;医药卫生—外科学] R442.2[医药卫生—诊断学;医药卫生—临床医学]
  • 作者机构:[1]滨州医学院附属医院,山东滨州256603, [2]滨州医学院中西医结合学院,山东烟台264003, [3]沙土镇新兴卫生院,山东菏泽274000, [4]桓台县人民医院,山东淄博256400
  • 相关基金:国家自然科学基金项目(81473612);山东省自然科学基金项目(ZR2009CL001);滨州医学院科技计划项(BY2010KJ018)
中文摘要:

目的:探讨胃肠舒片治疗骨科术后便秘的疗效。方法:共观察骨科术后便秘患者120例,随机分为两组,治疗组口服胃肠舒片,对照组口服复方芦荟胶囊,对比观察两组临床疗效、治疗前后便秘症状总积分和单项症状积分变化及药物毒副作用。结果:治疗组临床治愈率为60%,对照组为40%,治疗组治愈率显著高于对照组(P〈0.05),治疗后治疗组便秘主要症状总积分为2.22±0.97,明显低于对照组总积分3.18±1.08。治疗后治疗组便秘症状单项积分分别为:大便性状0.52±0.11,排便难度0.50±0.13,排便间隔时间0.48±0.09,每次排便时间0.47±0.04,排便不尽或肛门阻塞感0.25±0.06,对照组便秘症状单项积分分别为:大便性状0.71±0.13,排便难度0.84±0.22,排便间隔时间0.81±0.15,每次排便时间0.79±0.08,排便不尽或肛门阻塞感0.38±0.03,治疗组便秘症状各单项积分均显著低于对照组(P〈0.05),两组均未见明显毒副作用。结论:胃肠舒片治疗骨科术后便秘具有疗效好,无明显毒副作用的优势。

英文摘要:

Objective: To investigate efficacy and side effects of Weichangshu tablets in the treatment of orthopedic postoperative constipation. Methods:120 patients with orthopedic postoperative constipation were randomly divided into two groups. The patients in the treatment group were treated with Weichangshu tablets, and the patients in the control group were treated with compound Luhui cap- sules. Then the clinical efficacy was observed and compared, including major changes of symptom scores and side effects of these medi- cations. Results: The clinical cure rate of the treatment group was 60%. It was significantly better than that of the control group (40%)(P〈0.05). Total score of the main symptoms of constipation of the treatment group (2.22±0.97) was significantly lower than that of the control group (3.18±1.08) (P〈0.05). The score of the individual symptom of the treatment group were significantly lower than that of the control group (P〈0.05). The score were respectively bowels character 0.52±0.1lvs 0.71± 0.13, defecate difficulty 0.50± 0.13 vs 0.84± 0.22,time interval of defecation 0.48± 0.09 vs 0.81± 0.15, time of each defecation 0.47± 0.04 vs 0.79± 0.08, feel of endless defecate or anus blocking 0.25± 0.06 vs 0.38± 0.03. The two groups showed no obvious side effects. Conclusions: Weichangshu has significant curative effect in treatment of orthopedic postoperative constipation, without significant side effects.

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期刊信息
  • 《现代生物医学进展》
  • 中国科技核心期刊
  • 主管单位:黑龙江省卫生厅
  • 主办单位:黑龙江省红十字医院 黑黑龙江省红十字医院 黑龙江省森林工总医院
  • 主编:申宝忠
  • 地址:哈尔滨市南岗区花园街184号403
  • 邮编:150001
  • 邮箱:biomed_54@126.com
  • 电话:0451-82583800 53658268
  • 国际标准刊号:ISSN:1673-6273
  • 国内统一刊号:ISSN:23-1544/R
  • 邮发代号:14-12
  • 获奖情况:
  • 国内外数据库收录:
  • 被引量:33230