阿片依赖是一种慢性、反复发作性脑疾病.本文综述了阿片类物质依赖、戒断和复吸各个阶段下丘脑-垂体-肾上腺皮质轴的改变,及其与阿片依赖、戒断和复吸的关系.
Opioid dependence is a chronic, repeated relapsing disease in brain. This review focuses on the changes in hypothalamie -pituitary -adrenal axis in opioid dependence, withdrawal and relapse, and the relationship between HPA axis and opioid addiction.